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BACKGROUND

As part of a £8 million award from the MRC, industry and University of Birmingham, we have established a state-of- the-art metabolic phenotyping (metabolomics) facility to conduct medical research including the development of stratified medicine approaches. Phenome Centre Birmingham (PCB), which was formally opened on 23 May 2016 by the UK Government's Chief Scientific Advisor Sir Mark Walport (http://www.birmingham.ac.uk/news/latest/2016/05/Phenome-Centre-Birmingham.aspx), is applying eleven new liquid chromatography-mass spectrometers (LC-MS), two new Bruker 600 MHz NMR spectrometers, liquid handling robots and high specification computational infrastructure to better understand metabolic perturbations in human health, disease and ageing. The facility is anticipated to conduct tens of thousands of analyses of human samples per year, creating genuinely "Big Data", with extensive clinical metadata. It is based alongside one of the largest hospitals in Europe, the Queen Elizabeth Hospital at Birmingham, and the new £24 million Institute of Translational Medicine. In addition, the PCB will interact closely with the MRC-NIHR National Phenome Centre in London and the new international network of Phenome Centres to enhance metabolic phenotyping in the UK and globally.

RESPONSIBILITIES & REQUIREMENTS

We seek a highly motivated bioinformatician to join the 10-person PC-B team and contribute to fulfilling the research objectives of this centre with a focus on developing, implementing and applying bio- and chemo-informatics tools for the integration and analysis of clinical metadata and NMR spectroscopy metabolic phenotyping data; tools for metabolite identification; and/or statistical bioinformatics. This will include implementing automated data processing pipelines, contributing to experimental design, undertaking statistical and computational analyses, and interpretation of large scale metabolomics datasets. Further opportunities include collaborating with clinical scientists and contributing to training courses in the Birmingham Metabolomics Training Centre (http://www.birmingham.ac.uk/bmtc).

Applicants should hold a PhD (awarded) in computational metabolomics, chemoinformatics, bioinformatics, biostatistics or a closely related area, with experience and demonstrated success of working independently and as part of a large team in a bioanalytical or academic research facility in industry or academia as well as having a growing national reputation in metabolomics and/or bioinformatics/biostatistics.

TERMS

The post is available in the first instance for 3 years with the expectation for significant extension subject to the success of Phenome Centre Birmingham.

LOCALE

Birmingham, United Kingdom

HOW TO APPLY

Informal enquiries can be addressed to Professor Mark Viant (tel: +44 (0)121 414 2219 or email: M.Viant[at]bham.ac.uk) or Dr Warwick Dunn (tel: +44 (0)121 414 5458 or email: W.Dunn[at]bham.ac.uk).

For further information or to apply visit [Job ID Number - 51678]: http://www.hr.bham.ac.uk/jobs

DEADLINE

3rd January 2017

Discussion forums: Opportunity: Bioinformatics/Biostatistics Research Fellow (in NMR Metabolomics) (#51678) @ University of Birmingham -- Birmingham, UK

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