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RESPONSIBILITIES

Highly motivated developer/web developer to build a cutting-edge web resource of mutation signatures. We have an exciting opportunity for a developer/web developer to work with Dr Serena Nik-Zainal on a new central public resource to hold, display and mine mutation signatures as well as potentially find new ones. The role will primarily focus on front-end web development, in conjunction with a dedicated back-end developer, together with our team of highly motivated scientists, software developers, and database specialists. The successful candidate will be involved in all stages of the design and implementation of this modern distributed web resource. The goals of the project are two-fold: 1, Provide a web application to support the querying and mining of the catalogue of mutation signatures and 2, Design and implement a back-end compute infrastructure to allow external users to analyse their own data using our in-house signature detection software. The role is supported by the COMSIG consortium, funded by a Wellcome Trust Strategic Award, which is focused on exploring the mutational signatures of DNA damage and repair processes. The over-arching objective of the project is to explore mutational signatures in the context of the biological mechanisms associated with DNA repair, by integrating cellular/molecular approaches with genome-wide assays including genomic sequencing, RNA-seq and ChIP-seq. The position would suit a highly motivated developer/web developer who has an interest in building cutting edge web resources to store, display and mine highly complex biological data sets. We are looking for an individual who enjoys working in a highly motivated multi-disciplinary team environment and can help solve the complex IT problems that will ultimately aid our understanding of mutation processes.

REQUIREMENTS

Essential Skills:

Good degree in Bioinformatics, IT or Computer Science
Web development experience, using HTML5, CSS, and javascript
Enjoy working as part of a team
Scripting skills in Python or Perl
Working, developing and compiling software tools in a UNIX/LINUX environment

PREFERENCES

Ideal Skills:

Understanding of requirements for developing secure web applications
Experience of relational databases (Oracle, MySQL) and NoSQL databases
Experience of working with "cloud" technologies such as VMware, OpenStack or Amazon Web Services (AWS)
Experience of handling Next Generation sequencing data
Experience of statistical analysis in a bioinformatics
Experience of workflow management IT systems
LSF or Open Grid scheduling software
Experience of working in an Agile Software Development Group
Background in cancer genetics

COMPENSATION

Salary range: £31,033 to £39,142 pa depending on experience.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

ABOUT US

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society. To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

HOW TO APPLY

Please apply via: https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=290978

Please state your current salary in the covering letter.

DEADLINE

Closing date for applications: 11th January 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.

POLICY

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Discussion forums: Opportunity: Developer/Web Developer -- COMSIG Consortium @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

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