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Opportunity: Postdoctoral Associate -- Cancer Evolution @ The Jackson Laboratory -- Farmington, CT (US)
Submitted by Tyler Chukwu; posted on Friday, December 16, 2016
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BACKGROUND
About The Position:
Dr. Roel Verhaak's lab at The Jackson Laboratory for Genomic Medicine is currently seeking two recent graduates interested in investigating cancer and therapy resistance.
We are looking for a molecular biologist experienced in cell culture and lentiviral transfection who will be investigating the evolution of individual glioblastoma (GBM) cells using single cell barcoding technology and comprehensively characterized GBM model systems. The goal of this study is to trace clonal evolution in GBM, to evaluate the genomic properties of dominant, therapy resistant clones relative to therapy sensitive cells and to compare findings in model systems with observations from clinical tumors. The ideal candidate has affinity for data analysis but experience with sequencing data (-analysis) is not a requirement.
We are also looking for computational biologists or researchers from associated disciplines to strengthen our computational analysis group. We offer a wide range of projects, including studies of extrachromosomal DNA in the context of cancer evolution which involves long read sequencing analysis; DNA methylation and transcriptome single cells studies; nucleosome analysis; and longitudinal analysis of glioma patient samples.
About the Verhaak Lab: Our group is highly interdisciplinary and provides a collaborative and fast-paced environment on the forefront of cancer genomics, in a scientific environment that will suit every ambition. Our laboratory has been involved with (and has led) several studies of The Cancer Genome Atlas (Verhaak et al, Cancer Cell 2010; Brennan/Verhaak et al, Cell 2013; Brat/Verhaak et al, N Eng J Med 2015; Cecarelli et al, Cell 2016; Zheng et al, Cancer Cell 2016). Check out our Biorxiv preprints for more current work (http://biorxiv.org/content/early/2016/12/03/091173 and http://biorxiv.org/content/early/2016/10/14/081158). The Jackson Lab for Genomic Medicine is home to a large number of postdocs both at the bench and the command line, with several world class PIs.
About JAX-GM: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, the brand new JAX-GM conveniently sits midway between NYC and Boston in the heart of Connecticut. JAX-GM is part of an exciting $1.1 billion venture between the state of Connecticut and The Jackson Laboratory, an internationally-recognized research and educational institution with unparalleled genomic resources and research support services.
REQUIREMENTS
- PhD in relevant field of study
- Background in cancer research and/or computational biology required.
- At least 2 first author publications in peer-reviewed journals (including submitted manuscripts) required.
- Research experience in one or more of these areas highly preferred: tumor evolution, therapy resistance, brain tumors, single cell sequencing.
COMPENSATION
Salary and benefits are highly competitive. Our Postdoctoral Associates enjoy distinct advantages, including:
- A uniquely collaborative environment that fosters interdisciplinary "team science" without departmental barriers
- Unparalleled genomic resources and superior research support services
- Close interaction with our award-winning faculty members
- Partnerships with leading universities and medical centers
- Numerous courses and conferences focused on genetics, genomics and biomedicine
- Exceptional benefits, ample time off and other valuable programs
- Working for an institution that has repeatedly been voted among the top 15 "Best Places to work in Academia" in the world by readers of The Scientist
DEADLINE
ASAP until filled.
POLICY
EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.
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