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BACKGROUND
The Center for Infection and Immunity in the Mailman School of Public Health at Columbia University - one of the world's most advanced academic centers focused on microbial surveillance, discovery and diagnosis has an immediate opening for Sr. Programmer Analyst in Bioinformatics for developing pipelines to analyze large-scale gene expression datasets. The successful applicant will join a dynamic laboratory consisting of approximately 50 personnel at Columbia University and a global network of researchers that work on projects related to infectious disease surveillance and discovery in humans and wildlife, host response to infections, microbiome research and large-scale studies on autism and chronic fatigue syndrome/myalgic encephalomyelitis.DUTIES & RESPONSIBILITIES
- Provide bioinformatic support for projects related to microbial detection and discovery – 40%
- Provide bioinformatics support for RNA-Seq analysis, transcriptomics in a large and dynamic laboratory – 40%
- Manage databases – 10%
- Contribute to publications and research grants – 5%
- Perform other related duties as assigned – 5%
REQUIREMENTS
The candidate is expected to demonstrate the following skills and experience:- Advanced knowledge of bioinformatics, statistics, systems biology, including biological pathway and network analysis, with working knowledge of writing pipelines for analysis of gene expression data from Illumina sequencing platform
- Thorough knowledge of NGS experimental design, data quality control, mapping software such as Bowtie, BWA or STAR, normalization and clustering methods, Tuxedo Suite tools such as Tophat and Cufflinks, Gene Set Enrichment Analysis, Ingenuity Pathway analysis and UCSC genome browser
- Experience with genome annotations from major bioinformatics resources (NCBI, UCSC)
- Ability to work in Unix environments consisting of high performance clusters
- Advanced understanding of multi-threading tools (SGE, MPI), resource management and allocation
- Broad knowledge scripting languages, such as Shell, Python, Perl and R in an academic or industrial environment. Proficiency in R and Bioconductor packages is desirable.
- Requires a bachelor's degree in bioinformatics or computer science and at least four years of experience in bioinformatics.
- Master's degree with 2 years of related experience
COMPENSATION
Salary will be competitive and commensurate with experience. Columbia University offers a comprehensive and attractive benefits package (Benefits Highlights for Officers 2015 – http://hr.columbia.edu/benefits/bib)HOW TO APPLY
Please visit https://jobs.columbia.edu/applicants/Central?quickFind=159512
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