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BACKGROUND

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to the Wellcome Genome Campus Courses, Conferences and Public Engagement (CCPE) programme. The CCPE programme delivers training and engagement focussed around genomics, its applications, and implications. Its vision is to inspire a range of audiences both on the Campus and beyond it, and make the world of genomics open and accessible to all. To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre. Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus. Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

RESPONSIBILITIES

We are seeking a software developer to join the Human Genetics Informatics (HGI) team at the Wellcome Trust Sanger Institute. HGI is an agile development team responsible for providing efficient access to cutting-edge analysis methods to human genetics faculty groups at the Sanger Institute. Skilled developers are encouraged to apply regardless of prior job experience, as the focus is on coding and core computer science skills rather than on work experience. Recent graduates or current students in their final year are especially encouraged to apply, although it is essential that any candidate has substantial development experience outside of coursework (e.g. active participation in open source projects or the pursuit of personal coding projects). An interest in scientific research and a strong intellectual curiosity are also necessities, although a formal education in genetics is not required. Our team's focus is the development and operation of scientific analysis workflows and tools for genetic data analysis, as well as developing the infrastructure necessary to manage the efficient operation of those workflows. This role will involve working as part of the HGI team to deliver working systems that produce analytical outputs for human genetics faculty research groups within the Sanger. Team members will be expected to produce quality code; to be able to work both independently and closely with colleagues to develop, debug, and optimize their code; and to be comfortable communicating directly with scientific researchers regarding requirements. As part of the HGI team, the successful applicant would have access to Sanger's world-class computational resources, including a 15000+ core computational cluster, an OpenStack private cloud environment, and many petabytes of high-speed distributed filesystems and object stores. The choice of development language depends on the task at hand, so as a small team we are flexible in terms of what languages we use. The ideal applicant would be comfortable with independently learning the basics of a new language in a matter of days, and to become productive in it within a week or two. Our philosophy is that development skills are independent of language and that programming languages shouldn't generally need to be formally taught. That said, a successful applicant will likely have developed expertise in at least a few languages as a side-effect of previous development projects, and should be able to demonstrate skill in at least one scripting/interpreted and one compiled language.

REQUIREMENTS

Degree in Computer Science or in a related quantitative field (e.g. Mathematics, Physics, Bioinformatics) coupled with substantial experience in software development (although not necessarily in a work context)
Knowledge of core computer science concepts (e.g. object oriented design, memory management, algorithm implementation) and practices (e.g. version control, agile development, extreme programming)
Skill in a combination of interpreted and compiled languages (e.g. C, Go, Haskell, Java, Perl, Python, R, Ruby, Scala)
Experience producing useful code (not necessarily in the context of employment - personal projects or contributions to open-source projects would be equally applicable)
Critical thinking skills and a familiarity with statistics (e.g. statistical distributions, significance tests, inference)
Knowledge of Linux/POSIX based operating systems, libraries, and tools
Good communication skills
Attention to detail
An interest in scientific research and a strong intellectual curiosity

PREFERENCES

Experience in genetics, bioinformatics, or a related field
Experience in development of free open-source software
Experience in an academic software development environment
Experience with user interface design, especially using modern web-based technologies (e.g. "HTML5")
Experience working with hypermedia-driven REST APIs
Knowledge of advanced computer science concepts and algorithmic techniques (e.g. agent-based computing, artificial intelligence, dynamic programming, game theory, Gibbs sampling, hidden Markov models, information theory, and machine learning)
Experience with relational and non-relational databases (e.g. MongoDB, CouchDB, Titan, OrientDB, Cassandra, MySQL/MariaDB, PostgreSQL)
Experience with virtualisation/containerisation technologies (e.g. CernVM, Docker, LXC, OpenStack)

COMPENSATION

Salary up to £39729 plus excellent benefits. A market supplement of £1,465 per annum (non-pensionable) may also be available; this is dependent on skills and experience and is offered in recognition of the current market value of certain skills and technologies. Market supplements are subject to periodic review.

HOW TO APPLY

Click on the link https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=297364

DEADLINE

15th February 2017

Discussion forums: Opportunity: Senior/Software Developer -- Human Genetics Informatics @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

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