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    Opportunity: Director, Childhood Cancer Data Lab for Computational Biologist/Bioinformatics PhD @ Childhood Cancer Data Lab -- Suburban Philadelphia, PA (US)
    Submitted by Kathy Muscarella; posted on Tuesday, April 11, 2017

    BACKGROUND

    Overview:
    Located in the Philadelphia area, The Childhood Cancer Data Lab (CCDL) is a new program of Alex's Lemonade Stand Foundation (ALSF) that will use big data to advance childhood cancer research. As a leader in childhood cancer awareness and research, ALSF identifies areas of need then creates and funds programs to fill those needs. The Childhood Cancer Data Lab is the latest program creation.

    What is Alex's Lemonade Stand Foundation?
    Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of cancer patient Alexandra "Alex" Scott (1996-2004). In 2000, 4-year-old Alex announced that she wanted to hold a lemonade stand to raise money to help find a cure for all children with cancer. Since Alex held that first stand, the Foundation bearing her name has evolved into a national fundraising movement, complete with thousands of supporters across the country carrying on her legacy of hope. To date, Alex's Lemonade Stand Foundation, a registered 501(c)(3) charity, has raised more than $140 million toward fulfilling Alex's dream of finding a cure, funding over 690 pediatric cancer research projects throughout North America. Learn more about these funded projects at https://www.alexslemonade.org/where-money-goes.

    RESPONSIBILITIES

    The Director of the Childhood Cancer Data Lab will work with the ALSF executive team, with guidance from the ALSF Scientific Advisory Board, to make the CCDL a reality. You will help develop the vision, then implement the plan, for the CCDL. You will inspire, lead and innovate, building a successful team that uses data as a tool to fight childhood cancer while becoming part of the childhood cancer research community. This is an outstanding opportunity for an innovative researcher to create an amazing program that will have a significant impact on the childhood cancer community.
    • Launch CCDL as a startup; assist with development of strategy and a 5-year plan. This will include strategies for cataloging and as necessary gathering data, harmonizing data, and developing a scalable strategy for data storage and access.
    • Oversee the building of a team to launch the CCDL. The size of the team will scale in direct proportion to the 5 year plan.
    • Assume responsibility for CCDL staff as needed, including recruiting, supervising, mentoring, and personal development.
    • Work with ALSF team to design a permanent home for the CCDL.
    • Oversee projects performed by computational biologists within the CCDL.
    • Partner with major pediatric cancer genomics efforts world-wide to enable access to extant data as well as be aware of prospective projects generating big data.
    • Develop new and/or deploy existing pipelines and algorithms to evaluate other experimental data (e.g., drug synergy experiments, chemical screens, CRISPR screens).
    • Lead 'omics data mining from providing scientific inputs of experimental design to data analysis, interpretation, and hypothesis generation.
    • Develop computational solutions for the identification of novel cancer therapeutic targets.
    • Produce high quality scientific reports, presentations and papers.
    • Maintain expertise and awareness in state-of-the-art cancer genomics science, computational biology methods, and relevant external genomics data sources.
    • Actively seek, evaluate and champion the adoption of new approaches to expand the team's capabilities.
    • Innovate, motivate and inspire others in a team-oriented, collaborative environment.
    • Provide support for advanced computational tasks in the lab.
    • Get to know thought leaders within the childhood cancer community and communicate the plan for CCDL.
    • In years 2 and beyond, become intimately aware of the ALSF grants program and opportunities for collaboration. Develop a strategy to prospectively plan for ALSF grant applicants to engage the CCDL as part of their research plan. Develop methods for prospective collaboration.
    • As necessary, explore opportunities for active collaboration with major academic or industry partners, especially in the areas of data storage and high performance computing.
    • NO grant writing needed - ALSF is investing the resources to make the CCDL a reality!

    REQUIREMENTS

    • PhD in Computational Biology or related field
    • 5 or more years of experience as a computational biologist/ scientist
    • Knowledge of cancer biology and/or cancer genomics; experience with pediatric cancer research preferred
    • Experience in current methods of bioinformatics; experience developing pipelines for analysis of biologic data highly desirable
    • Knowledge of high-performance computing and cloud-computing technologies
    • Proficiency with coding in R, Python or other similar languages
    • Experience with big data including data summary visualization
    • Effective communication skills
    • Ability to assign tasks, work independently
    • Strong organizational techniques, including the ability to handle a variety of tasks in a fast-paced environment
    • Significant experience working in a scientific research setting
    • Management experience
    • Authorization to work in the US for any employer

    LOCALE

    Suburban Philadelphia, PA, USA

    COMPENSATION

    This full-time opportunity offers a competitive salary and benefits package.

    HOW TO APPLY

    Interested candidates should submit a CV/resume with cover letter describing your interest and why you would be the right fit for this position to humanresources[at]alexslemonade.org.

    DEADLINE

    Until position is filled.

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