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    Opportunity: Senior Software Developer -- Cancer and Ageing @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK
    Submitted by Sam Bowker; posted on Saturday, September 30, 2017


    Highly motivated Software Developer required to develop Virtualised Infrastructure for Big Data Genome analysis using OpenStack.

    An exciting Software Development opportunity has become available to further develop our software infrastructure to help in the Group's aim of increasing our understanding of cancer and ageing. The position will be based in the IT Team in the Cancer, Ageing and Somatic Mutation (CASM) Division at the Wellcome Trust Sanger Institute.


    Specifically, the role will involve developing a virtualised compute infrastructure to allow our analysis workflows to be run in a distributed, adaptable and scalable environment. This position would suit a Software Developer who enjoys developing software solutions for large scale data analysis. The software needs to be efficient, flexible and under Continual Integration to ensure resilience.

    We are looking for an individual who enjoys working in a multi-disciplinary team environment to help solve complex IT issues which will ultimately aid our understanding of cancer and ageing in humans.


    • Good degree in the areas of Bioinformatics, Mathematics, Physics or Computer Science
    • Software development skills
    • Enjoy working as part of a team


    • Experience of OpenStack, VMware or Amazon Web Services (AWS)
    • Experience of any of the following technologies, Docker, Vagrant, Packer, Ansible and the HashiCorp Suite (Nomad, Consul, Vault, Terraform)
    • Software development using a compiled language (C,C++,Java)
    • Experience of development in a Continual Integration environment
    • Experience of workflow management IT systems
    • LSF or Open Grid scheduling software
    • Experience of handling Next Generation sequencing data
    • Ability to work independently, organise own workload and meet tight deadlines
    • Ability to communicate ideas and results effectively
    • Keen to learn and share ideas and knowledge
    Although experience of software development or bioinformatics would be an advantage, applications are welcome from enthusiastic and committed graduates or candidates from other fields who wish to pursue a career in bioinformatics whilst carrying out a challenging and rewarding role.


    Permanent contract.


    £38,000-£39,729, plus excellent benefits.

    Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.


    The CASM Support IT team has successfully developed a suite of algorithms to analyse genetic variation in cancer genome data. This includes software to detect tumour genetic variation (e.g. single-base substitutions, structural rearrangements, copy number changes) and the ability to annotate the resulting variants and mine the data for interesting patterns and signatures ( The CASM Division has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers ( The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

    The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.


    Clicking on the following link[...]26493

    Please include a covering letter and CV with your application.


    29th October 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.


    Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

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