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    Research: GEN: First nanopore sequencing of human genome
    Submitted by J.W. Bizzaro; posted on Monday, January 29, 2018

    Submitter

    EXCERPT

    For the first time, researchers using a nanopore sequencer have assembled a human genome using ultra long reads. This achievement, described today in Nature Biotechnology, marks a milestone for the technology, as well as a considerable step toward eventually completing the human genome.

    "The ability to do this is significant," Matthew Loose, Ph.D., associate professor of medicine at the University of Nottingham and one of the lead authors on the paper, tells GEN. "This is the first time it's been possible to generate enough data on a nanopore sequencer to perform a de novo assembly of the human genome." Using the Oxford Nanopore Technologies (ONT) MinION sequencer, the team generated over 91.2 Gb of sequence data, or 30x coverage of the genome. They achieved single reads of up to 882 kb, with over half the reads coming in at more than 100 kb.
    Source: www.genengnews.com/gen-[...]01044

    Paper: www.nature.com/articles/nbt.4060 (open)

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