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    Opportunity: Therapeutic Discovery Information Scientist @ LifeArc -- Stevenage, UK
    Submitted by Helen Adams; posted on Monday, February 12, 2018


    LifeArc is pioneering new ways to turn great science into greater patient impact. We bring together a network of partners to tackle specific diseases and directly fund academic and early stage research.

    Our Centre for Therapeutics Discovery (CTD) in Stevenage operates at the interface between academic research and the drug discovery industry. We take novel academic targets and generate lead stage small molecules and therapeutic antibodies for indications with unmet medical need.

    We are looking for a highly motivated individual who will support a multidisciplinary team of Computational and Medicinal Chemists, Biologists and Antibody Engineers by maintaining and developing our scientific data platforms and helping to develop a truly bespoke informatics facility at LifeArc.


    You will be responsible for maintaining and developing our Dotmatics Browser web-based interface which enables our scientists to query and visualise project data from the multiple data sources we maintain.

    This will require you to develop and support ODBC, API links and ETL protocols for extraction and cleansing information from all our corporate data repositories where our biological data on small molecules, proteins and antibodies is currently stored. These cover a multiple set of data sources including structured databases such as our Activity Base, Genedata and Bioregister, Electronic Lab Notebooks, Chemical Inventories and other unstructured legacy formats.

    Working with our team you will also help build and enrich our informatics platform by providing tools to enable dynamic access to and analysis of scientific data and up-to-date information from reliable public data sources. This includes annotations for our compounds from ChEMBL and protein targets, pathways and disease associations with information from Uniprot and the Human Protein Atlas.


    The successful candidate will preferably have a BSc degree in Biological or Chemical Science and ideally have an MSc in Bioinformatics (or be close to completing). Applications from newly qualified PhD graduates in a relevant field are also welcome.

    You will be expected to demonstrate knowledge of a range of programming tools (such as Python/Perl, JavaScript, java, web-services, Pipeline Pilot or KNIME) and a good grasp of rational databases and some appreciation of statistical packages (e.g. R).

    Excellent communication skills, with the ability to work collaboratively with our scientists and IT specialists are key requirements of the role. In addition, you will have excellent time-management skills with the ability to prioritise and manage a busy workload.


    Your salary will be determined by qualifications and experience. In addition, LifeArc offers a defined contribution pension scheme, private health insurance, a flexible benefits scheme and 31 days paid holiday per year.


    To apply, please email your CV and covering letter explaining why you want to work for LifeArc to: recruitment[at] or by post to Recruitment, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX (electronic applications preferred).


    Closing date: 11 March 2018


    LifeArc is committed to the principles and practices of equal opportunities and to encouraging the establishment of a diverse workforce. It is our policy to employ individuals on the basis of their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion or belief. This includes creating a culture that fully reflects our commitment to equal opportunities for all.

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