[Next-Generation Sequencing Book]
  • [Photo] Eugene McDaid • April 17, 2018

    BACKGROUND

    This is a great opportunity for an experienced bioinformatician with expertise in analysing microbial genomes, ideally in a metagenomics context. The ideal candidate will be an enthusiastic individual looking to play a key role in building a new biotech company and to contribute to the development of a new class of medicines.

    RESPONSIBILITIES

    The successful candidate will be responsible for the development of methods and workflows to enable the annotation and interpretation of genomes and metagenomes associated with healthy and diseased states. Studies will be undertaken with large clinical datasets using metagenomics and AI to define microbiome bacterial signatures associated with disease and drug response and constituting potential therapies or diagnostics. This is an opportunity to be involved at the early stages of this novel area of microbiome biomedicine and to help shape the informatics and analytics of the company to meet the needs of this new discipline. Innovation and problem-solving will be required and actively encouraged.

    Key duties will include:
    • Develop and run methods, metrics, and pipelines for the automatic functional annotation of genomic and microbiome data
    • Develop tools and databases capable of integrating and comparing large-scale (meta)genomics datasets and their associated metadata
    • Collaborate in multi-disciplinary projects to perform end-to-end data analysis toward therapeutic discovery and development
    • Identify, develop and implement new analytical, statistical and machine-learning methods to improve and extend our informatics platform

    REQUIREMENTS

    Candidate Specifications:
    Essential:
    • PhD or Masters in Bioinformatics or related discipline, or equivalent experience
    • 5 years of experience in bioinformatics and/or sequence data analysis
    • Demonstrable experience of microbial genomics and/or metagenomics
    • Proficiency in a high-level programming language, eg; Python or Perl
    • Familiarity with Linux command-line environment
    • Good communication and presentation skills
    • Flexibility to work in a new and dynamic company
    • Role holder will be an independent self-starter, looking to learn and acquire new skills
    • Candidates must be legally entitled to work in the UK
    Desirable:
    • Familiarity with phylogenetic/taxonomic classification of genomes and metagenomes
    • Experience with gene, protein and pathway annotation tools and databases
    • Knowledge of machine learning
    • Background in statistics
    • Familiarity with other `omics' data: transcriptomics, metabolomics, etc
    • Experience with running analyses on high-performance compute: farms, clusters, or cloud

    COMPENSATION

    There are some great benefits available with this role as well as the opportunity to work with some of the best minds in genomics and software development.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Programming, Python, Perl, Software, Version Control, Linux, Jenkins, Git, Chef, Puppet, Bioinformatics, Genomics, Metagenomics, Microbiome, Machine Learning, Statistics, Cambridge.

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