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BACKGROUND

A Postdoctoral Research Associate position is available in the Division of Epidemiology, Department of Medicine, from Vanderbilt University Medical Center. Our current research concentrates on population-based genetic epidemiologic studies for the exploration of putative causative genetic risk variants and genes for cancers using bioinformatic and functional genomics approaches. We will focus on numerous genetic epidemiology and large genomics studies using large population-based prospective cohort studies. We will apply and develop bioinformatics tools and build statistical models to process large whole genome sequencing and whole exome sequencing, RNA-seq, array-based genotype and epigenetic data to investigate all types of genetic variants including coding/noncoding and structure variants for understanding the underlying molecular mechanisms of cancerigenesis. The successful candidate will lead independent research projects in genetics, epigenetics, functional genomics, and bioinformatics fields. The successful candidate will also expect to participate in multiple collaborative projects in cancer-related genetic epidemiology studies.

RESPONSIBILITIES

Under guidance from Dr. Xingyi Guo, the candidate is expected to work in a wide range of bioinformatics projects.

REQUIREMENTS

PhD in bioinformatics, computational biology, biostatistics, genomics, molecular biology or related fields. The successful candidate should have strong background in processing high-throughput genomic and genetic data with biostatistics knowledge.
Strong experience with script languages such as Perl, Python or R and the Linux/Unix environment is required.
Experience in statistical computing (e.g. R/Bioconductor and Biopython)
Good interpersonal skills
Excellent in English both in writing and speaking

COMPENSATION

Salary is commensurate according to the NIH pay level. The postdoc positions will be provided with the benefits following Vanderbilt University Medical Center standard.

ABOUT US

The Division of Epidemiology is committed to conducting research to enhance and expand our understanding of the distribution and determinants of disease, to promoting collaboration aimed at the translation of research into cost-effective strategies of disease prevention and health care delivery, and to training independent investigators in epidemiology research and disease prevention. Our group has a broad interest in the research of genetics and genomics for cancer studies. We concentrate on population-based genetic epidemiologic studies for the exploration of novel genetic risk variants and genes for cancer outcomes. These projects will primarily build from valuable cohort resources based at the Vanderbilt Epidemiology Center, i.e., the Asian Breast Cancer Consortium (ABCC) and the Asia Colorectal Cancer Consortium (ACCC). We are interested in developing and applying computational methods for processing high-throughput genomic sequencing data from the above population-based cohorts to identify various genetic variants, especially structure variants for cancer risk. In particular, we are also highly interested in studying the functional potential of risk coding or noncoding variants by integrated big experimental data from next-generation sequencing (e.g., ChIP-seq, ATAC-seq, BS-seq and RNA-seq) from public databases (i.e. ENCODE). Information about the Division of Epidemiology can be found at https://medicineandpublichealth.vanderbilt.edu/vec/our-team/index.php.

HOW TO APPLY

To apply, please send cover letter, CV, summary of past work, and the names and email addresses of three references to Dr. Xingyi Guo at xingyi.guo[at]vanderbilt.edu. The position will be for two years with the possibility of further extension.

DEADLINE

The deadline for applications is July 30, 2018. Any applications received after this time or incomplete will not be considered.

POLICY

Vanderbilt University Medical Center wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.

Discussion forums: Opportunity: Postdoctoral fellow in Bioinformatics/functional genomics/genetic epidemiology -- Division of Epidemiology @ Vanderbilt University Medical Center -- Nashville, TN (US)

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