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BACKGROUND
Job Summary/Basic Function:
The Functional and Chemical Genomics Program at the Oklahoma Medical Research Foundation (OMRF, omrf.org) is inviting applications for Staff Scientist positions. The selected candidates will help lead collaborative projects. OMRF is a non-profit private foundation dedicated to fundamental, interdisciplinary research and to the translation of knowledge to medicine. Research interests within FCG include fundamental questions emerging from ongoing high-throughput genetic and epigenetic studies of disease using the latest technologies in genomics, functional genomics, model system biology, and chemical biology. The Program occupies newly renovated space designed to foster highly collaborative and innovative research using genetic model systems including C. elegans, Drosophila, planaria, zebrafish, mice, and stem cells. Our strategy aims to embrace the post-genomic era in scaling the functional analysis of genetic and epigenetic alterations underlying human disease. OMRF researchers have access to state-of-the-art facilities and outstanding core technology laboratories including Imaging, Next-generation Sequencing, Clinical Genomics, and more.
Three specific interdisciplinary project opportunities include:- Dr. Wan Hee Yoon and Dr. Gaurav Varshney are collaborating on a project to model human diseases carrying OGDH family genes. Fellows undertaking this project will emerge with expertise in Drosophila genetics and CRISPR/Cas-9 targeting in zebrafish.
- Dr. David Jones, Dr. Jian Li, and Dr. Magdalena Bieniasz are collaborating on a project examining a novel role of HSF1 and its aberrant activation in cancer. Fellows will have the opportunity to develop expertise in utilization of patient-derived xenograft (PDX) tumor models, to determine programmatic transcriptional targets of HSF1 and its connection to known oncogenes and tumor suppressor genes.
- Dr. David Forsthoefel, Dr. Wan Hee Yoon, and Dr. David Jones are collaborating on a project examining the roles of Xbp1 in stem cells, regeneration, innate immunity, and cancer. Fellows involved in this project will help define the mechanistic roles of Xbp1 and novel proteostasis regulators in planaria, Drosophila, and zebrafish.
REQUIREMENTS
Minimum Qualifications:- Ph.D. in a biological science, chemistry, physics or other relevant area, M.D., or equivalent.
- Doctorate
TERMS
Classification: Ongoing
Status: Full-TimeCOMPENSATION
We offer attractive salaries & comprehensive benefits package, view our benefits here: https://omrf.org/about-omrf/human-resources/benefits/HOW TO APPLY
Interested candidates should apply online at http://apptrkr.com/1305739
Posting Number: 0001185
Department: Functional and Chemical Genomics
Discussion forums: Opportunity: Several Staff Scientist Openings @ Oklahoma Medical Research Foundation -- Oklahoma City, OK (US)
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