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    Opportunity: Senior Computational Chemist @ A leading player in the drug discovery field -- Toulouse, France
    Submitted by Eugene Mc Daid; posted on Friday, January 18, 2019



    Paramount Recruitment are working with a leading player in the drug discovery field who are growing their computational chemistry capabilities in an attractive and dynamic city in South France. This company have been established almost 30 years and has leading scientists, state-of-the-art technologies as well as key therapeutic expertise such as neuroscience, immunology metabolic diseases, oncology and infectious diseases. The company intends to develop best-in-class and first-in-class differentiated therapeutics and has long standing relationships with many of the worlds top 20 pharmaceutical companies. The company operates worldwide, but has their HQ in Europe along with more than 5 offices and 200 employees.

    This role is for a Senior Computational Chemist to join the team in a full time, permanent position. Within the Research Informatics Department, you will work in collaboration with the Chemistry Department in Medicinal Chemistry projects.


    • Providing drug discovery and drug design support to small molecule projects and realize key contributions in hit identification, hit to lead and lead optimization
    • Providing Cheminformatics support to screening and medicinal chemistry teams for virtual screening, hits analysis, hits expansion, libraries design, scaffold hopping, QSAR and ADMET modeling, multi-parametric optimization
    • Interacting constructively with internal and collaborative project teams
    • Adapting the scientific knowledge for solving research problems with the help of line managers and team leaders to achieve key milestones
    • Gathering and diffusing pertinent news, methods and tools from the scientific literature in computational chemistry
    • Presenting your own work at project meetings, and department meetings
    • Writing and contributing to publications and patents where possible


    Desirable Knowledge, Skills and Abilities:
    • PhD in Computational Chemistry, Cheminformatics or related area
    • 3-5 years + experience in drug design and discovery from a biotech, pharmaceutical or academia
    • Expertise in computational drug discovery and drug design of small molecules
    • Good knowledge of software packages and technologies used in computational chemistry and drug design, including MOE, ChemAxon, CCDC packages, and Knime.
    • Good knowledge of therapeutic targets classes including kinases, GPCRs, enzymes, proteases, ion channels
    • Good knowledge of the main chemical and biochemical databases including PDB, CSD, ChEMBL, DrugBank, PubChem
    • Excellent project management and analytical capabilities
    • Strong communication skills and ability to communicate effectively with clients


    Please don't hesitate to contact Jade for more information at jpage[at] or on +44 121 616 3472!

    Keywords: Computational Chemistry, Cheminformatics, Drug Discovery, Small Molecules, Drug Design, South of France, French, Europe

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