BACKGROUND

RESPONSIBILITIES

• Providing drug discovery and drug design support to small molecule projects and realize key contributions in hit identification, hit to lead and lead optimization
• Providing Cheminformatics support to screening and medicinal chemistry teams for virtual screening, hits analysis, hits expansion, libraries design, scaffold hopping, QSAR and ADMET modeling, multi-parametric optimization
• Interacting constructively with internal and collaborative project teams
• Adapting the scientific knowledge for solving research problems with the help of line managers and team leaders to achieve key milestones
• Gathering and diffusing pertinent news, methods and tools from the scientific literature in computational chemistry
• Presenting your own work at project meetings, and department meetings
• Writing and contributing to publications and patents where possible

REQUIREMENTS

• PhD in Computational Chemistry, Cheminformatics or related area
• 3-5 years + experience in drug design and discovery from a biotech, pharmaceutical or academia
• Expertise in computational drug discovery and drug design of small molecules
• Good knowledge of software packages and technologies used in computational chemistry and drug design, including MOE, ChemAxon, CCDC packages, and Knime.
• Good knowledge of therapeutic targets classes including kinases, GPCRs, enzymes, proteases, ion channels
• Good knowledge of the main chemical and biochemical databases including PDB, CSD, ChEMBL, DrugBank, PubChem
• Excellent project management and analytical capabilities
• Strong communication skills and ability to communicate effectively with clients

HOW TO APPLY