[Next-Generation Sequencing Book]
  • [Photo] Eugene McDaid • April 10, 2019

    BACKGROUND

    This is a great opportunity for a strong bioinformatician/ analyst to join a world-renowned institute who are pioneering new approaches for noninvasive molecular diagnostics and analysis of cancer genomes and evolution. The ideal candidate will have a strong NGS background, with particular experience in ctDNA.

    The organisation work with large collections of patient material from different clinical studies, which are analysed by both genome-wide methods and targeted methods for sensitive mutation detection, with the aim to develop novel tools for cancer diagnostics by developing improved methods and demonstrating clinical utility. Furthermore, they explore the biophysical properties of ctDNA with the aim of identifying its origins and interactions.

    RESPONSIBILITIES

    The successful candidate will work closely with the other bioinformaticians in the group to develop and maintain databases and streamline analysis pipelines to ensure timely delivery of results. They will also support non-computational members of the group in devising and implementing project specific analyses.

    REQUIREMENTS

    Skills Required:
    • A good biological background and excellent computing skills
    • Experience in the analysis of sequencing data using software such as GATK is essential.
    • Experience in variant calling from DNA sequencing data
    • Experience in linux based operating environments
    • Experience in use of high-performance computing
    • Very good general data analysis and programming skills
    • Background in cancer research (or relevant topic)
    • Previous experience in the use of statistical software such as R
    • General knowledge of machine learning, classification, and statistics methods, including algorithms and software packages
    • Demonstrated experience in reproducible practices such as the use of git
    Experience Required:
    • Database design and management
    • Good programming and scripting skills, algorithm/software design
    • Analysis of next-generation sequencing data, genomics/evolution or relevant
    • Computational analysis of high-throughput molecular biology experiments
    • Experience in consulting with non-computational research scientists on experimental design and bioinformatics analysis
    • Experience with computational systems and data storage platforms

    TERMS

    3-year Fixed-Term

    COMPENSATION

    There are some great benefits available with this position including a competitive salary and the chance to work with some of the brightest minds in the industry, looking to revolutionise the way healthcare is carried out in the UK.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Bioinformatics, Analyst, Genomics, NGS, ctDNA, WGS, GATK, Variant, Calling, Linux, HPC, Analysis, Computational, Cancer, Algorithm, Git, Platforms, Cambridge

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