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    Opportunity: Scientist II, Bioinformatics @ Astellas Institute of Regenerative Medicine (AIRM) -- Marlborough, MA (US)
    Submitted by Emily Bibler; posted on Friday, August 16, 2019


    The Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

    Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be a part of Astellas, a company with a uniquely collaborative and patient-focused culture. There's something special about working at Astellas. It's reflected in our focus on the people we serve, the way we treat each other and the results we achieve together as a company.

    AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms – both embryonic and induced pluripotent stem cells as well as other cell based therapy research programs. AIRM is headquartered in Marlborough, Massachusetts.

    We are seeking a highly motivated and talented bioinformatician to join our R&D team and contribute to development of stem cell based therapies spanning multiple therapeutic areas. The successful candidate will have a track record of success in a collaborative research environment with a strong scientific background in biology and analysis of next generation sequencing data.


    Essential Job Responsibilities:
    • Apply computational algorithms, software tools and data mining techniques for bioinformatics analysis of NGS data.
    • Refine existing analysis pipelines/tools and implement new strategies/resources for analysis and visualizations to address changing project needs.
    • Provide support to non-computational R&D scientists seeking to independently use established bioinformatics resources.
    • Interpret results, prepare presentations and reports for technical and non-technical audiences.
    • Assist with infrastructure support for data collection, storage and analysis.


    • PhD (3+ years) or MS (7+ years) with degree in in bioinformatics, computational biology, computer science or other relevant discipline. Title commensurate with experience.
    • Strong scientific background in biology and NGS
    • Hands-on experience with NGS data analysis with expertise in differential expression and single cell processing
    • Proficiency with a variety of programming languages for statistical computing and generation of graphics
    • Fluency in at least one scripting language (i.e.: Python, Perl, Groovy)
    • Excellent communication and interpersonal skills and ability to effectively collaborate with other teams
    • Excellent work planning, organization and record keeping is essential


    • Experience with AWS or other cloud vendors
    • Experience with ChIP-seq and small RNA Seq
    • Proficient in aseptic mammalian cell culture
    • Experience with nucleic acid/protein isolation, RT-PCR and other standard molecular biology techniques


    Type: Full-time
    Category: Research and Development


    Marlborough, MA


    Apply using the following URL:[...]=true


    Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled


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