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    Opportunity: Senior Bioinformatician @ An exciting, fast-paced therapeutics organisation -- London, UK
    Submitted by Eugene McDaid; posted on Wednesday, November 06, 2019



    This role offers the opportunity for a Senior Bioinformatician to join an exciting, fast-paced therapeutics organisation focusing in oncology, immunology and neuroscience. This opportunity offers the chance to work with cutting-edge technologies including antibody repertoire profiling and deep learning.

    The VC-backed company is at an early stage. It aims to deliver a pipeline of targets and therapeutic candidates, with goals to become a transformational large and small molecule therapeutics organisation, meaning a successful candidate will have the opportunity to help build and grow with the company.

    The Role:
    A successful candidate will work alongside the scientific team and will have a foundational role in building the company's platform, working closely with the founders and collaborators to build core components of the end-to-end bioinformatics approach, establishing standards and practices. The successful candidate will also be involved in patient stratification and management, analysis and visualisation of large scale omics data. You will work within a virtual team to support target identification. As the company grows, you will support the scientific leadership team to build, further coordinate and establish the technology platform & team. This role will report to the Chief Technology Officer (CTO).


    • Perform analysis of human disease datasets for example large‐scale omics datasets including antibody/B cell receptor sequencing.
    • Develop computational models to stratify patient groups, evaluate antibody repertoires and enable data‐driven target discovery.
    • Support team to build and maintain a secure data management platform.
    • Advise on and support activities to functionally validate targets using in silico approaches (e.g., FGWAS, GWAS).
    • Work collaboratively with the team including bioinformatics research groups and external partners.
    • Communicate efficiently, interpret, summarise and visualise data for presentation to different audiences.
    • Keep current on new discoveries and changes in methodologies and approaches that might enhance the platform.
    • Work closely with the scientific leadership team to help build the platform and team.


    • A PhD (or in exceptional cases, a masters level degree) in computer science, bioinformatics or related discipline
    • Experience at working with large‐scale genomic or functional genomic datasets
    • Proficient with R and Python
    • Mastery in integrating and analysing diverse high‐dimensional omics data sets relevant for immunology, oncology and neurodegeneration
    • Experience in building infrastructure for large scale data analysis and storage
    • An ambition to work with the team to build a transformative company
    • A team player who proactively and directly communicates and collaborates with other team members


    • 5+ years of industry experience
    • Pre‐existing network of relevant external scientific contacts
    • Evidence of contribution to and influence of the strategic scientific direction of a large group


    There are great benefits on offer with this role including a competitive salary, pension, holidays and more.


    Please do not hesitate to contact Harvey Uppal at huppal[at] or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Bioinformatics, Oncology, Immunology, Neuroscience, Target, Therapeutics, Deep Learning, Python, Genomics, Analysis, Infrastructure, In Silico, GWAS, RNA Seq, Single-Cell, London

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