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    Opportunity: Bioinformatics Scientist @ Arizona State University -- Tempe, AZ (US)
    Submitted by Elaina Thomas; posted on Friday, November 22, 2019

    BACKGROUND

    The Biodesign Center for Personal Diagnostics (CPD) in the Biodesign Institute within Arizona State University's Knowledge Enterprise is seeking an experienced PhD-level Bioinformatics Scientist who will provide bioinformatics expertise to our highly diverse and active research groups in production and analysis of genome-scale data to gain insights on human physiology and diseases. This position is primarily for a large-scale project funded by DARPA, which will focus on epigenomics-based predictive modeling (biodesign.asu.edu/news[...]ction).

    Our center is specialized in biomarker research aided by sophisticated genomics and proteomics applications and equipped with fully automated robotic systems for gene cloning, microarray production/processing, as well as next-generation DNA sequencers. We also have a strong expertise in developing high-throughput assays, biomarker panels/signatures, and predictive modeling for various health-related applications. In addition, we are operating web applications for public data and resource repositories, such as the plasmid repository DNASU (dnasu.org/DNASU/Home.do) and the BioSpecimen Commons (biospecimencommons.org). To operate and support the high-paced research activities, we are working closely with the Genomics and Bioinformatics Core at ASU and provide bioinformatics supports to both on- or off-campus researchers in a broad aspects of research projects, including genomics, proteomics, machine-learning, and statistics.

    RESPONSIBILITIES

    As a member of bioinformatics team at CPD, you will:
    • Participate mainly in a DARPA-funded multi-institutional multi-omics project aiming to develop epigenetic signatures and predictive models for detecting exposure to various types of hazardous agents by using bioinformatics, statistics, and machine-learning approaches.
    • Lead analysis of systems-level data such as next-generation sequencing and single-cell sequencing for the DARPA and other basic and translational research projects at CPD.
    • Participate in writing reports, manuscripts, and grant proposals.
    • Support and collaborate with both internal and external researchers.

    REQUIREMENTS

    Minimum Qualifications:
    • PhD in science or related fields with experience in biological research projects and translational and basic science, experimental design, data analysis, and instrumentation.
      • Assistant Research Scientist level: PhD degree and 3 years of experience
      • Associate Research Scientist level: PhD degree and 5 years of experience
      • Research Scientist level: PhD degree and 7 years of experience
    • Hands-on research experience in analyzing high-content biological data (e.g. next-generation sequencing or high-throughput screening data), preferentially epigenetics data
    • Must hold a US Citizenship and eligible to handle CUI (controlled and unclassified) data
    Working Environment:
    • Regular activities require ability to manage multiple tasks at one time, to be able to prioritize tasks; to manage conflict; to interact in a team environment; and to communicate through verbal and written work.
    • Activities are performed in an environmentally controlled office setting and laboratory subject to extended periods of sitting, keyboarding and manipulating a computer mouse; required to stand for varying lengths of time and walk moderate distances to perform work.
    • Frequent bending, reaching, lifting, pushing and pulling up to 25 pounds.
    • Regular activities require ability to quickly change priorities, which may include and/or are subject to resolution of conflicts.
    • Ability to clearly communicate verbally, read, write, see and hear to perform essential functions.
    • May be required to wear personal protective equipment before entering laboratories such as lab coat, gloves, safety glasses, closed toe shoes, and respirator.

    PREFERENCES

    Desired Qualifications:
    • PhD degree in bioinformatics, computational biology, biostatistics, genomics, molecular biology or related fields, and a proven track record of novel research
    • Research experience in biomarker discovery, statistical modeling, and/or machine-learning
    • Proficiency in scientific programming/scripting (e.g., Python or Java), bioinformatics/biostatistics packages (e.g., R/Bioconductor and Biopython), and SQL database
    • Knowledge on biological databases (e.g. gene annotations, pathways, and interactomes) and genomic/proteomic data resources (e.g. NCBI, Ensembl, COSMIC, and UniProt)
    • An efficient team player with strong communication, presentation, and interpersonal skills
    • Detail oriented, flexible, self-motivated, excellent troubleshooting skills
    • Experience in writing scientific documents (e.g. reports, manuscripts and grant proposals)
    • Wet lab experience in molecular and cellular biology
    • Experience in development of scientific software and databases
    • Experience in high-content data visualization/analysis (e.g. network analysis)
    • Excellent written and verbal communication skills; able to articulate compelling and impactful science
    • Adept at working in interdisciplinary scientific teams

    COMPENSATION

    Salary: Depends on experience.

    ABOUT US

    Department Statement:
    For the fourth year in a row, ASU has been named the most innovative school in the nation, recognizing the university's culture of groundbreaking research and partnerships, as well as its commitment to helping students thrive in college and beyond. U.S. News and World Report have named ASU as the most innovative university all four years the category has existed.

    The Office of Knowledge Enterprise Development is committed to Advancing Research, Innovation, Entrepreneurship and Economic Development. We seek research funding, support faculty researchers, nurture partnerships with external partners, promote innovation and entrepreneurship, and share what we learn with the community and the world. We make discovery possible. research.asu.edu.

    The Biodesign Institute addresses today's critical global challenges in healthcare, sustainability, and security by developing solutions inspired from natural systems and translating those solutions into commercially viable products and clinical practices.

    The Biodesign Center for Personalized Diagnostics is a research center within the Biodesign Institute that focuses on personalized medicine. Promising advances in the area of personalized medicine have shown us that life-threatening diseases are as distinct in character as the individuals they afflict. The Virginia G. Piper Center for Personalized Diagnostics has been established with an eye toward overcoming the health care challenges posed by disease variance. Our Center is developing new diagnostic tools to pinpoint the molecular manifestations of disease based on individual patient profiles. The strategy promises not only to improve therapeutic care, but also to greatly reduce treatment costs by allowing for early disease detection.

    About ASU:
    Arizona State University is a new model for American higher education, an unprecedented combination of academic excellence, entrepreneurial energy and broad access. This New American University is a single, unified institution comprising four differentiated campuses positively impacting the economic, social, cultural and environmental health of the communities it serves. Its research is inspired by real world application blurring the boundaries that traditionally separate academic disciplines. ASU serves more than 90,000 students in metropolitan Phoenix, Arizona, the nation's fifth largest city. ASU champions intellectual and cultural diversity, and welcomes students from all fifty states and more than one hundred nations across the globe.

    HOW TO APPLY

    Applicants are responsible for including a cover letter, CV, and the names of three professional references in their application through the Interfolio website: apply.interfolio.com/71623. Emailed applications will not be accepted.

    Application deadline is December 31, 2019. Applications will continue to be accepted on a rolling basis for a reserve pool. Applications in the reserve pool may then be reviewed in the order in which they were received until the position is filled.

    DEADLINE

    Close date: 12/31/2019

    POLICY

    ASU is a tobacco-free university. For details visit www.asu.edu/tobaccofree

    AmeriCorps, Peace Corps, and other national service alumni are encouraged to apply.

    Arizona State University is a VEVRAA Federal Contractor and an Equal Opportunity/Affirmative Action Employer. All qualified applicants will be considered without regard to race, color, sex, religion, national origin, disability, protected veteran status, or any other basis protected by law.

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