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BACKGROUND

This is a great opportunity working with a well-funded early stage biotech company who have identified novel tumour-specific antigens derived from reactivated endogenous retroviral sequences. They are using this discovery to enable the development of a range of pharmaceutical products including vaccines, biologics and cell therapies. Importantly, these pharmaceuticals are non-personalised and thus able to broadly impact the needs of oncology patients.

This is an exciting opportunity to join an organisation that aims to support efforts to acquire and interrogate immunopeptidomic data from primary human tissue in order to discover, validate and quantify novel cancer-specific (neo) antigens. The ideal candidate will oversee the processing and analysis the genomic pipeline used to identify cancer-specific transcripts. They will be responsible for the analysis of genomics and transcriptomic data using existing software packages and through the development of novel algorithms. They will also be responsible for integrating data output for further analysis.

A successful candidate will have a PhD in Bioinformatics or a related subject and have an interest in the developing field of immuno-oncology. You will also have a working knowledge of genomics methods and the ability to work with NGS data in a HTC environment.

REQUIREMENTS

Experience of software development in a life sciences commercial/academic environment
Knowledge of R and/or Python scripting languages
Knowledge of genomic data analysis, specifically RNA Seq

In addition to the above, the following skills/experiences are desirable:

Experience with version control systems e.g. Bitbucket
Practical knowledge of workflow management e.g. Snakemake, Nextflow
Experience of the Amazon Web Services (AWS) environment
Knowledge of Database Development/Management

Additional criteria include:

The ability to communicate results clearly and effectively and to discuss scientific ideas within the work environment
An active interest in supporting scientific research
The ability to work on several projects in parallel
Excellent record keeping and precision driven work approach
The ability to work in a team

COMPENSATION

There are great benefits on offer with this role including a competitive salary, pension, holidays and more.

HOW TO APPLY

Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

Keywords: Bioinformatics, Bioinformatician, Genomics, Pipelines, RNA, Python, Version Control, Bitbucket, Snakemake, AWS, Database, Development, London, Immunology, Oncology, NGS

Discussion forums: Opportunity: Bioinformatician @ A well-funded early stage biotech company -- London, UK

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