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    Opportunity: Bioinformatician @ A well-funded early stage biotech company -- London, UK
    Submitted by Eugene McDaid; posted on Tuesday, January 14, 2020



    This is a great opportunity working with a well-funded early stage biotech company who have identified novel tumour-specific antigens derived from reactivated endogenous retroviral sequences. They are using this discovery to enable the development of a range of pharmaceutical products including vaccines, biologics and cell therapies. Importantly, these pharmaceuticals are non-personalised and thus able to broadly impact the needs of oncology patients.

    This is an exciting opportunity to join an organisation that aims to support efforts to acquire and interrogate immunopeptidomic data from primary human tissue in order to discover, validate and quantify novel cancer-specific (neo) antigens. The ideal candidate will oversee the processing and analysis the genomic pipeline used to identify cancer-specific transcripts. They will be responsible for the analysis of genomics and transcriptomic data using existing software packages and through the development of novel algorithms. They will also be responsible for integrating data output for further analysis.

    A successful candidate will have a PhD in Bioinformatics or a related subject and have an interest in the developing field of immuno-oncology. You will also have a working knowledge of genomics methods and the ability to work with NGS data in a HTC environment.


    • Experience of software development in a life sciences commercial/academic environment
    • Knowledge of R and/or Python scripting languages
    • Knowledge of genomic data analysis, specifically RNA Seq
    In addition to the above, the following skills/experiences are desirable:
    • Experience with version control systems e.g. Bitbucket
    • Practical knowledge of workflow management e.g. Snakemake, Nextflow
    • Experience of the Amazon Web Services (AWS) environment
    • Knowledge of Database Development/Management
    Additional criteria include:
    • The ability to communicate results clearly and effectively and to discuss scientific ideas within the work environment
    • An active interest in supporting scientific research
    • The ability to work on several projects in parallel
    • Excellent record keeping and precision driven work approach
    • The ability to work in a team


    There are great benefits on offer with this role including a competitive salary, pension, holidays and more.


    Please do not hesitate to contact Harvey Uppal at huppal[at] or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Bioinformatics, Bioinformatician, Genomics, Pipelines, RNA, Python, Version Control, Bitbucket, Snakemake, AWS, Database, Development, London, Immunology, Oncology, NGS

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