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    Opportunity: Cancer Bioinformatician -- 2 year fixed-term @ A world-leading institute -- Sutton, UK
    Submitted by Eugene McDaid; posted on Tuesday, February 04, 2020



    This position is a great opportunity for a strong Bioinformatician to join a world-leading institute in their cancer therapeutics unit. The role focuses on the development and provision of broad, state-of-the art bioinformatics analysis to support drug discovery and will involve both applying bioinformatics and the development of pipelines to support these. The successful applicant will be exposed to, and contribute to, all aspects of drug discovery and will be responsible for supporting specific drug discovery projects, interacting with biologists, software developers and bioinformaticians.


    • Evaluate and apply broad bioinformatics analysis expertise to support drug discovery in the CTU.
    • Contribute to drug discovery projects by analysing genomic, transcriptomic or proteomic data using established and state-of-the-art approaches.
    • Evaluate and tailor such approaches and create bioinformatics pipelines for specific drug discovery project requirements.
    • Deploy bioinformatics pipelines using scripting languages such as Perl/Python and statistical packages such as R.
    • Perform GSEA and other suitable downstream analyses required to help the biological interpretation of complex data with view to aid decision making in drug discovery projects.


    • Proven work experience of applying bioinformatics analyses (2 years minimum)
    • Proven experience in analysing large scale genomic, transcriptomic or proteomic data
    • Proven experience in interpretation of large scale data including the application of Gene Set Enrichment Analysis (GSEA)
    • Proven experience of developing scripts to enable bioinformatics workflows
    • Proven experience in cancer informatics
    • Established skills in the application of broad bioinformatics analysis tools and databases including gene and protein sequence analysis and annotation tools
    • Skilled in using statistical analysis packages such as R or Matlab
    • Good working knowledge of Unix and shell/bash
    • Proven scripting skills using a scripting language such as Python and/or Perl
    • Good applied knowledge of complex bioinformatics pipeline suites including NGS analysis pipelines such as Broad Best Practice pipeline or good applied knowledge of proteomic analysis tools such as MASCOT, OpenMS or equivalent
    • Establishment and execution of bioinformatics pipeline on High-Throughput Computing infrastructure


    There are some great benefits on offer with this role including a competitive salary, strong pension, generous holidays and more.


    Please do not hesitate to contact Harvey Uppal at huppal[at] or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Cancer, Genomics, Bioinformatics, NGS, Proteomics, Drug, Discovery, Transcriptomics, Pipelines, Perl, Python, Data, Science, Analysis, Workflows, Shell, Bash, HPC, Sutton, Surrey

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