[Next-Generation Sequencing Book]
  • [Photo] Wei Dai • May 8, 2020

    BACKGROUND

    Our group has a long-standing expertise in multi-omics studies using sequencing technology. We offer an open, supportive, dynamic and motivating academic environment with the possibility to work on cutting edge research project. We use a wide spectrum of approaches for translational cancer study including whole-genome sequencing (WGS), whole-exome sequencing (WES), whole-genome bisulfite sequencing (WGBS), ChIP-seq, Hi-C, ATAC-seq, RNA-seq and single cell sequencing.

    We are looking for an enthusiastic and highly motivated applicant holding, or about to obtain, a BSc. or MSc. degree in bioinformatics, computational biology or similar. Preference will be given to applicants with previous experience in one or more of the following areas: RNA-seq, ChIP-Seq, Hi-C, integrative analyses from multiple omics datasets.

    References:
    1. Zheng H, Dai W, Cheung AK, Ko JM, Kan R, Wong BW, Leong MM, Deng M, Kwok TC, Chan JY, Kwong DL, Lee AW, Ng WT, Ngan RK, Yau CC, Tung S, Lee VH, Lam KO, Kwan CK, Li WS, Yau S, Chan KW, Lung ML: Whole-exome sequencing identifies multiple loss-of-function mutations of NF-kappaB pathway regulators in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2016, 113(40):11283-11288.
    2. Dai W, Zheng H, Cheung AK, Tang CS, Ko JM, Wong BW, Leong MM, Sham PC, Cheung F, Kwong DL, Ngan RK, Ng WT, Yau CC, Pan J, Peng X, Tung S, Zhang Z, Ji M, Chiang AK, Lee AW, Lee VH, Lam KO, Au KH, Cheng HC, Yiu HH, Lung ML: Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2016, 113(12):3317-3322.
    3. Leong MML, Cheung AKL, Dai W, Tsao SW, Dawson WD, Lung ML: Epstein-Barr virus modulates a histone bivalent switch to suppress DNA damage repair pathway expression in squamous epithelial cells. Proc Natl Acad Sci U S A. 2019, 116(28):14144-14153.

    LOCALE

    Hong Kong

    HOW TO APPLY

    Please send your application including a cover letter, your CV, certificates of your qualifications, transcripts, your publication list and the contact details of at least two referees to Dr. Wei Dai (weidai2[at]hku.hk).

Discussion forums: Opportunity: PhD student Fall 2020 in Computational Cancer Biology @ University of Hong Kong -- Hong Kong

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PhD student Fall 2021 in Computational Cancer Biology
Submitted by Wei Dai ; posted on Tuesday, March 2, 2021
Our group in the Department of Clinical Oncology at The University of Hong Kong has a long-term interest in the multi-omics translational studies in cancers. We offer an open, supportive, dynamic and motivating academic environment with the possibility to work on cutting edge research project. We use a wide spectrum of approaches for translational cancer study including whole-genome sequencing (WGS), whole-exome sequencing (WES), whole-genome bisulfite sequencing (WGBS), ChIP-seq, CUT&RUN, Hi-C, ATAC-seq, RNA-seq and single cell sequencing. We are looking for an enthusiastic and highly motivated applicant holding, or about to obtain, a Master degree in bioinformatics, computational biology or similar. Preference will be given to applicants with previous experience in one or more of the following areas: RNA-seq, ChIP-Seq, Hi-C, integrative analyses from multiple omics datasets. HOW TO APPLY Please send your application including a cover letter, your CV, certificates of your qualifications, transcripts, your publication list and the contact details of at least two referees to Dr. Wei Dai (weidai2[at]hku.hk).

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