BACKGROUND

We are seeking a talented, highly motivated Bioinformatics Research Scientist to lead our bioinformatics pipeline and develop innovative solutions for analyzing and visualizing omics data related to innate immune signaling projects. The candidate will work both collaboratively and independently on projects within the Kanneganti lab in the Department of Immunology. The candidate will lead cutting-edge computational analyses of omics datasets including proteomics, RNAseq, and microarray data, along with other needs as they are identified. The candidate will ensure the highly effective and accessible end results of these projects, as well as the scientific accuracy and robustness.

Candidates with a strong background in transcriptomic and proteomic data analysis are highly encouraged to apply for this position. Successful candidates will have excellent critical thinking, problem-solving and data management skills and a keen attention to detail.

St. Jude Children's Research Hospital offers a unique environment with clinical and basic science investigators working in close proximity and interacting regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider joining St. Jude.

The laboratory of Dr. Thirumala-Devi Kanneganti is internationally renowned for its expertise in cellular signaling in the immune system. We are particularly interested in dissecting the signaling pathways involved in innate immunity and cell death, with a focus on NLRs and inflammasomes, and understanding how these pathways connect to adaptive immunity (T cells). Dr. Kanneganti's lab offers a fast-paced research environment focused on the innate immune system, including an opportunity to collaborate with researchers in the departments of Immunology, Infectious Diseases, Oncology, and beyond. Generous salary support and a benefits package are available. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, microarray and RNA-seq analysis of gene expression, transgenic/knock-out technology, and animal facilities from biosafety level 2 to enhanced biosafety level 3.

Please see the following publications:
Cell (2020) 181(3):674-687.e13.
Nature (2019) 573(7775):590-4.
Nature Microbiology (2019) 4(2):316-27.
Cell (2018) 173:1--14.
Journal of Experimental Medicine (2018) 215(4):1023-34.
Nature (2016) 540:583-7.
Science Immunology (2016) 1(2):aag204-5.
Cell (2015) 162(1):45-58.
Nature Immunology (2015) 16(5):467-75.
Immunity (2015) 42(4):654-64.
Nature (2014) 516(7530):246-9.
Nature (2013) 498(7453):224-7.

REQUIREMENTS

Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required
Ph.D which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software); OR If Ph.D with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required.
Experience with programming languages such as Perl, C, or Java required

BACKGROUND

REQUIREMENTS

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