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    Opportunity: Sr. Scientist, Bioinformatics @ Ribometrix -- Durham, NC (US)
    Submitted by Kevin de la Cruz; posted on Tuesday, April 27, 2021

    BACKGROUND

    Ribometrix is committed to delivering on the promise of addressing human disease through novel scientific insight into the structure of RNA. Unlike traditional drug discovery methodologies that target the product of RNA (proteins), we believe small molecule therapeutics can be designed to interact with RNA to deliver a meaningful therapeutic benefit to patients living with disease.

    We are a team of individuals driven by the spirit of innovation, collaboration, empowerment, and integrity who are committed to the goal of helping patients with our novel therapeutic approach.

    If you are looking for an opportunity to pioneer new science, collaborate with great people, and ultimately help those in need, then Ribometrix may be the place for you.

    We are seeking a highly motivated Senior Scientist to join our RNA Biology group and contribute to our bioinformatics capabilities. This person will be part of the bioinformatics team that is responsible for implementing and developing NGS software, developing and validating biological insights from complex datasets, and creating visualization methods and will have a key role in identifying and characterizing RNA targets for the Ribometrix platform. The position provides opportunities to collaborate extensively with other members of the RNA Biology, Lead Discovery, and Chemistry teams and to contribute to both the science and strategy of treating disease by targeting RNA. An ideal candidate will have experience with algorithm design for NGS data, have the capability to integrate genomics data in novel analyses, and have excellent understanding of key bioinformatic resources, including ontologies.

    RESPONSIBILITIES

    Responsibilities include but are not limited to:
    • Design algorithms to answer biological questions and validate with statistical methods.
    • Implement existing NGS software in workflows and develop software to meet unmet needs.
    • Create unique visualization methods to communicate results to wet-lab biologists and leadership.
    • Perform complex data analysis and interpretation to generate conclusions and next steps that drive the science forward.
    • Support multiple tasks and maintain attention to detail in a fast-paced environmentWork collaboratively and lead by example to promote our Ribometrix Core Values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

    REQUIREMENTS

    • BS in Bioinformatics or related field with 18+/ years experience; MS in Bioinformatics or related field and 15+ years experience; or PhD in Bioinformatics or related field and 6+ years experience (Level will be awarded commensurate with experience).
    • Extensive knowledge of next-generation sequencing (NGS) and associated technologies (e.g., RNA-seq) is required.
    • Experience integrating genomics and/or transcriptomics data types is required.
    • A track record of algorithm design is required.
    • Experience with RNA biology (e.g., mRNA quality control, RNA processing, or lncRNAs) is preferred.
    • Experience interrogating RNA structure, and/or analyzing RNA chemical modification data (e.g., SHAPE or DMS) is preferred.
    • Experience with SQL databases and/or interfacing with a LIMS system is preferred.
    • Strong initiative, problem solving skills, desire to learn, attention to detail, and ability to effectively organize and prioritize are required.
    • Ability to work independently and as part of a diverse and dynamic team is required.
    • Strong initiative, problem solving skills, desire to learn, attention to detail, and ability to effectively organize and prioritize are required.
    • Ability to work independently and collaboratively as part of a diverse and dynamic team is required.
    • Excellent interpersonal skills, professional maturity, proactive communication skills, and strong written and verbal communication and presentation skills are required.
    • Strong initiative complemented with a sense of accountability, sense of urgency and adaptability is required.
    • Experience working in drug discovery, especially in an industry setting, is preferred.
    • Previous experience in a startup/entrepreneurial environment is preferred.

    LOCALE

    Durham, NC USA 27709

    HOW TO APPLY

    Apply Here: www.click2apply.net/nVqV[...]IwRwB

    POLICY

    Ribometrix is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions of this position.

    Recruiting Agencies, Please Note:
    Ribometrix will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Ribometrix via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Ribometrix. No fee will be paid in the event the candidate is hired by Ribometrix as a result of the referral or through other means.

    PI134988491

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