[Next-Generation Sequencing Book]
  • [Photo] Charlie Hathaway • May 13, 2021

    BACKGROUND

    Mosaic Therapeutics (MOSAIC) was founded in 2020 as a wholly-owned subsidiary of Genome Research Limited (GRL) with the aim of applying a decade of ground-breaking work in the Sanger Institute's Translational Cancer Genomics Laboratory to identify selective vulnerabilities in cancer cells that can be exploited therapeutically. MOSAIC's formation was enabled and its activities are being driven by the vision and management of Mathew Garnett and Adrian Ibrahim. MOSAIC also continues to benefit as a result of strong support from GRL, as GRL's most recent start-up company. We are looking for a Senior Data Scientist to provide data science support across a range of drug discovery activities using advanced statistical and artificial intelligence algorithms incorporating large scale patient, genomic and functional datasets to guide drug discovery.

    Our capabilities are based on a unique twin platform of experimental CRISPR gene-editing in next-generation tumour organoids and advanced machine-learning and statistical algorithms to selectively identify and exploit the vulnerabilities of different types of cancers. We draw upon a breath of public and proprietary curated data, validated computational pipelines, together with our deep knowledge of cancer therapeutics to provide data-driven insights for cancer drug discovery. The team at MOSAIC have pioneered the use of drug and genetic screens in next-generation cancer models for drug discovery, have generated widely used reference datasets and analytical tools, and have extensive experience working with pharmaceutical partners to develop new targets and therapies.

    REQUIREMENTS

    • Use a range of computational skills to provide innovative solutions to complex biological problems to gain new insights into multiple aspects of drug discovery. In particular, you should be familiar with using advanced statistical and artificial intelligence algorithms to analyze large biological datasets.
    • You will be expected to work creatively as part of a multi-disciplinary team in a dynamic and rapidly evolving field, delivering high value IT solutions in a timely fashion.
    • Knowledge of in R, Python or similar
    • PHD in in computer science, bioinformatics, data science or related scientific discipline with experience working in academia or industry or equivalent experience
    • Eligibility to work in the UK

    TERMS

    Hours: Full-time
    Contract length: 12 months fixed term

    LOCATION

    Wellcome Genome Campus, Hinxton, UK

    COMPENSATION

    Salary: £37,865-£45,359
    Benefits: Details of benefits are available on application

    HOW TO APPLY

    Please submit your CV and cover letter addressing the following:
    • Your motivations for applying to this role
    • Your suitability for the role, using the information above and in the job description
    Apply now: https://mosaic-tx.com/join-our-team/senior-data-scientist/

    DEADLINE

    Applications will be reviewed on an ongoing basis and the role may close early if a successful appointment is made.

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