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    Opportunity: Principal Data Scientist @ Mosaic Therapeutics (MOSAIC) -- Hinxton, UK
    Submitted by Charlie Hathaway; posted on Friday, May 14, 2021


    Are you a Principal Data Scientist looking to join a start up with aims of improving cancer patient's lives through drug discovery?

    We are a tumour agnostic cancer therapeutics company that has been established, initially as a wholly-owned GRL entity funded through Innovate UK and GRL, to identify and exploit cancer vulnerabilities, delivering better medicines to patients. MOSAIC is in the process of raising the venture funds necessary to take the unique outputs of our existing programmes into drug discovery. We are looking for a Principal Data Scientist to use advanced statistical and artificial intelligence algorithms incorporating large scale clinical, genomic and functional datasets to guide cancer drug discovery.

    Our capabilities are based on a unique twin platform of experimental CRISPR gene-editing in next-generation tumour organoids and advanced machine-learning and statistical algorithms to selectively identify and exploit the vulnerabilities of different types of cancers. We draw upon a breath of public and proprietary curated data, validated computational pipelines, together with our deep knowledge of cancer therapeutics to provide data-driven insights for cancer drug discovery. The team at MOSAIC have pioneered the use of drug and genetic screens in next-generation cancer models for drug discovery, have generated widely used reference datasets and analytical tools, and have extensive experience working with pharmaceutical partners to develop new targets and therapies.


    • Experience using statistical and/or artificial intelligence approaches, including but not limited to linear regression models, machine learning (elastic net, lasso, ridge regression) and neural networks
    • Ability to prioritise multiple tasks
    • Advanced knowledge of programming in R, Python or similar
    • Experience in the analysis of large-scale genomic, function genomic or clinical datasets through the use of automated workflows
    • Understanding of current software development methodologies, e.g. Scrum/Agile, CI/CD, Concurrent Version Systems (e.g. Git)
    • Eligibility to work in the UK
    Please download and view the accompanying job specification for a detailed description of the role, responsibilities, and requirements and the candidate guide for more details about our work, environment, and benefits.


    Hours: Full-time
    Contract length: 12 months fixed term


    Wellcome Genome Campus, Hinxton, UK


    Salary per annum: £45,516-£54,524 + bonus
    Benefits: Details of benefits are available on application


    This is a unique opportunity to join a multidisciplinary team and contribute to a Cambridge start-up at the cutting-edge of drug discovery.

    Please submit your CV and cover letter addressing the following:
    • Your motivations for applying to this role
    • Your suitability for the role, using the information above and in the job description
    Applications will be reviewed on an ongoing basis and the role may close early if a successful appointment is made.

    Apply now:[...]tist/


    Closing date: 22nd June 2021

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