BACKGROUND:
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Bioinformatician II provides specialized consulting and data analysis services to researchers at the Fred Hutch and across the wider Fred Hutch/UW Cancer Consortium. This position requires the ability to work independently, manage multiple overlapping data analysis projects, and communicate effectively with faculty, post-doctoral fellows, and research staff on a wide range of topics in biology, analysis of next-generation sequencing data, sound experimental design, and data science.

RESPONSIBILITIES:
The Bioinformatician II reports to the Bioinformatics Shared Resource Manager, in association with the Director of the Genomics & Bioinformatics Shared Resources, and will work with Fred Hutch scientists to refine computational research questions, develop analytical processes applied to large genomic datasets, and provide timely results and documentation for processes used.

• Perform quality control and end-to-end analysis of large sequence datasets from diverse workflows
• Consult with researchers to refine research questions and to develop sound experimental designs
• Identify best-practice bioinformatics tools and strategies to meet the needs of proposed projects
• Provide figures and written sections describing methods and results for manuscripts, presentations, and grant applications
• Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows
• Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide training and support as users analyze and interpret results

REQUIREMENTS:

• MS or PhD in bioinformatics, computational biology, genetics, or related field
• At least three years' professional experience with computational analysis of complex sequence-based data sets including some of these assays: whole exome sequencing; targeted amplicon sequencing; somatic variant calling; bulk RNA-seq expression ; single-cell expression and immune repertoire profiling; CUT&RUN; ChIP-seq; ATAC-seq; or CRISPR/Cas9 knockout screens
• Demonstrated fluency in R or Python 3, ideally both
• Proficiency with Linux/Unix shell scripting (e.g., bash)
• Strong organizational skills, including the ability to manage and prioritize multiple competing tasks
• Excellent written and verbal communication skills

LOCATION:
This position requires regular, onsite at Fred Hutch's South Lake Union campus in Seattle, Washington. This position is not available for full-time remote work.

HOW TO APPLY:
Please submit your application with CV and cover letter via our online job board: https://careers-fhcrc.icims.com/jobs/19983/bioinformatician-ii/job?

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

POLICY:
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our HR Operations at HRops[at]fredhutch.org or by calling 206-667-4700.