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Opportunity: Bioinformatician in Immunogenetics (m/f/d) @ Max Planck Institute of Immunobiology and Epigenetics -- Freiburg, Germany
Submitted by Thomas Manke; posted on Tuesday, January 25, 2022
BACKGROUND
The Max Planck Institute of Immunobiology and Epigenetics is looking for a Bioinformatician in Immunogenetics. The position will be available in the Boehm department (http://www.ie-freiburg.mpg.de/boehm). The Boehm group addresses a number of cutting-edge research questions related to the development and evolution of the vertebrate immune system (for recent review see, Annu Rev Immunol 36, 19,2018; Annu Rev Anim Biosci 2, 259,2014; Nat Rev Immunol 13, 831,2013). To support these studies, we seek an experienced bioinformatician with a strong background in sequencing data analysis, statistics and, ideally, prior exposure to immunogenetics studies. This position is open immediately and funded for two years, with the possibility of extension
RESPONSIBILITIES
- Design of sequencing experiments
- Processing and quality control of NGS datasets of whole genome and amplicon bisulfite sequencing
- Discovery of differentially methylated regions
- Variant calling
- Analysis of differential gene expression (bulk and single-cell RNA) and gene module calling
- TCR clonotyping
- Analyses of sequence homologies and conservation
- Reference genome and transcriptome assembly and annotation in non-model organisms
- Phylogenetic and comparative genomics analyses
- Development and implementation of custom analysis pipelines in collaboration with wetlab scientists
REQUIREMENTS
We are looking for a dedicated and motivated team player with strong communication skills and good command of the English language, holding a MSc or PhD degree in bioinformatics or biology with a clear computational component. The successful applicant will have a proven record in the analysis of large, high-dimensional genome-wide datasets and computational skills (Python or R) in a Linux environment. Additional pluses include experience in the following:
- High-performance computing in a cluster environment (e.g. slurm)
- Modern software development, deployment (conda), and version control (git)
- Workflow management (snakemake) and documentation (notebooks)
- Advanced statistical data analysis
TERMS & COMPENSATION
- Salary according to your qualification and professional experience according to TVöD
- Social benefits in line with public service
- Professional training and development opportunities
- Challenging work in a modern working environment
- Family-friendly offers (affiliated day care center at the institute, parent-child room, breastfeeding room, pme family service
LOCATION
Located in a region that connects Germany, France and Switzerland, our institute offers an international research environment with outstanding infrastructure facilities and a positive working atmosphere that places a high value on work-life balance.
HOW TO APPLY
Have we sparked your interest? Please submit your complete application documents including a 1 page motivation summary, CV and contact details of referees via our online application portal at http://www.ie-freiburg.mpg.de by March, 31st, 2022.
For informal inquiries please contact: boehm[at]ie-freiburg.mpg
DEADLINE
March 31st, 2022
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