EXCERPT

> Researchers have developed an artificial intelligence model, TIGER, that predicts the on- and off-target activity of RNA-targeting CRISPR tools. This innovation, detailed in a study published in Nature Biotechnology, can accurately design guide RNAs, modulate gene expression, and is poised to drive advancements in CRISPR-based therapies.

Source: https://scitechdaily.com/artificial-intelligence-meets-crispr-the-rise-of-precision-rna-targeting-and-gene-modulation/

AVAILABILITY

Code to run Cas13d on-target and off-target TIGER models has been deposited on Github (https://github.com/daklab/tiger). A web-accessible version of TIGER is available at https://tiger.nygenome.org.