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    AI: SciTechDaily: Artificial intelligence meets CRISPR: the rise of precision RNA-targeting and gene modulation
    Submitted by J.W. Bizzaro; posted on Monday, July 03, 2023



    Researchers have developed an artificial intelligence model, TIGER, that predicts the on- and off-target activity of RNA-targeting CRISPR tools. This innovation, detailed in a study published in Nature Biotechnology, can accurately design guide RNAs, modulate gene expression, and is poised to drive advancements in CRISPR-based therapies.


    Code to run Cas13d on-target and off-target TIGER models has been deposited on Github ( A web-accessible version of TIGER is available at

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