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    Opportunity: Postdoctoral position in Bioinformatics, Genetic Epidemiology, Multi-omics and EHR @ Vanderbilt University Medical Center -- Nashville, TN (US)
    Submitted by xingyiguo; posted on Monday, January 08, 2024


    A Postdoctoral Research Associate position is currently open within the Division of Epidemiology, Department of Medicine at Vanderbilt University Medical Center (VUMC). Our research focus spans cancer etiology, prevention, precision medicine, and drug repurposing, employing advanced bioinformatics, statistical, machine learning, and deep learning methodologies. We also integrate multi-omics and Electronic Health Records (EHR) in our investigations. The lab has received funding from multiple NIH grants, including R37/R01 (i.e., NCI-funded transcriptome-wide association study and proteome-wide association studies in colorectal cancer). The Principal Investigator (PI) has authored >110 peer-reviewed publications, including recent high impact publications as lead author in Cancer Discovery, Gastroenterology, Journal of the National Cancer Institute, Nature communications, and American Journal of Human Genetics.

    Our ongoing research is centered on population-based molecular, genetic, and genomic epidemiologic studies aimed at identifying susceptibility genes, biomarkers and therapeutic drug targets for various cancers and diseases. We utilize and develop bioinformatics/statistical tools and pipelines to analyze extensive multi-omics data, including whole genome sequencing (WGS), whole exome sequencing (WES), RNA-seq, array-based genotyping, epigenetics, proteomics data, metabolomics, and single-cell omics data. We also conduct integrative analyses of omics data and develop natural language processing algorithms using resources from approximately 5.5 million patients' EHRs at VUMC. These efforts aim to provide potential avenues for the prevention and therapeutic intervention of human cancers and other diseases. The selected candidate will lead independent research projects focusing on statistical genetics, epigenetics, and bioinformatics in genetic epidemiology related studies.

    Please find more information about us @


    Under guidance from Dr Xingyi Guo, the candidate is expected to work on a wide range of Bioinformatics, Genetic Epidemiology, and Multi-omics projects. He/she should have:
    • A PhD in bioinformatics, genetic epidemiology, biostatistics, genomics/epigenetics, machine/deep learning or related fields.
    • Strong experience with script languages such as Python, Perl or R. Experience with the Linux/Unix environment is required.
    • Good knowledge in statistical computing or machine/deep learning.
    • Good interpersonal skills.
    • An excellent grasp of English, both in writing and speech.


    Salary is commensurate with the NIH pay scale. The postdoc positions will be provided with benefits following the VUMC standards.


    To apply, please send a cover letter, CV, summary of past work, and the names and email addresses of three references to Dr. Xingyi Guo at xingyi.guo[at]


    The Vanderbilt Epidemiology Center is committed to conducting research to enhance and expand our understanding of the distribution and determinants of disease, to promoting collaboration aimed at the translation of research into cost-effective strategies of disease prevention and health care delivery, and to training independent investigators in epidemiology research and disease prevention. The center has considerable strengths in international epidemiologic research and training and has close ties with multiple domestic and international institutions, furthering our mission to improve the health of human beings.


    VUMC wishes to reflect the diversity of society and welcomes applications from all qualified candidates, regardless of backgrounds and individual characteristics.

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