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    Research: Discovering Unknome Function (DUF) -- a DARPA research initiative
    Submitted by J.W. Bizzaro; posted on Monday, March 11, 2024

    Submitter

    The ARC Opportunity is seeking innovative approaches to tackle the challenge of the "Unknome" – a collection of genes that have been overlooked in research for over 20 years. These genes are difficult to study and often lack funding, leading to a research gap. The complexity of cellular processes and the labor-intensive nature of generating relevant datasets have hindered the development of models that can predict how genes affect cell behavior. The initiative is calling for high-throughput methods to accurately annotate these unknown genes, which could significantly advance our understanding of genetics.

    https://www.darpa.mil/ARC/DUF

    https://www.youtube.com/watch?v=AFOPZw8qAJc

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