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  • [Photo] AlloVista • April 6, 2026
    Bioinformatics Software Engineer – Founding Team
    Remote US
    $80-145K + equity
    Allovista * Remote (US) * Full-time or Senior Contract-to-Hire
    team[at]allovista.co

    ABOUT ALLOVISTA

    Allovista is building a cloud-native platform that lets clinical labs run multimodal MRD (measurable residual disease) detection in-house – replacing expensive send-out workflows with same-day, on-premise bioinformatics. Our stack processes amplicon sequencing, RNA-seq, and mass spectrometry data through automated pipelines, delivering concordance-scored clinical reports directly to physicians.

    We are pre-launch, post-funding, and looking for our first technical hire to help ship the MVP and validate with early-adopter labs.

    THE ROLE

    You'll work directly with the founder to build production bioinformatics pipelines and the React-based clinical interface. This is a high-ownership, generalist role – you'll touch everything from FASTQ processing to charting clonal frequency over time in D3.js.

    WHAT YOU'LL DO:
    • Design and implement AWS Step Functions pipelines for BCR/TCR repertoire analysis, variant calling, and MRD quantification
    • Build and validate bioinformatics workflows: alignment, clonotype identification, clone tracking, limit-of-detection analysis
    • Write and maintain analytical validation scripts – compare pipeline outputs against orthogonal methods and published benchmarks
    • Develop React UI components for clinical reporting: clonal tracking dashboards, MRD trend charts, concordance visualizations
    • Collaborate on database schema (PostgreSQL Aurora) for HIPAA-compliant sample and result storage
    • Participate in early customer discovery – join calls with lab directors, translate feedback into features
    • Help define QC thresholds, LOD criteria, and reporting standards for LDT (laboratory-developed test) workflows

    YOU SHOULD HAVE

    • 2+ years working with NGS bioinformatics (alignment, variant calling, or immune repertoire analysis)
    • Strong Python and/or R for data analysis and pipeline scripting
    • Hands-on experience with AWS services (Step Functions, Lambda, S3, Batch, or similar orchestration)
    • Proficiency in JavaScript/TypeScript and React (or willingness to ramp fast with strong JS fundamentals)
    • Familiarity with clinical sequencing data: FASTQ, BAM, VCF formats and QC metrics
    • Comfort working in a fast-moving, two-person team where you own entire features end-to-end

    BONUS POINTS

    • Experience with MRD detection, clonotype tracking, or immune repertoire profiling (ClonoSEQ, LymphoTrack, Adaptive, etc.)
    • Familiarity with D3.js or Recharts for data visualization
    • Background in clinical lab operations, LDT development, or CAP/CLIA compliance
    • Exposure to mass spectrometry proteomics or multi-omics integration
    • Contributions to open-source bioinformatics tools (Nextflow, nf-core, BioPython, etc.)

    COMPENSATION

    • Salary: $80,000 – $145,000 (commensurate with experience)
    • Equity: Meaningful founding-team equity stake (details shared during interviews)
    • Benefits: Remote-first, flexible hours, conference budget, equipment stipend
    • This can start as a senior contract engagement ($55--$75/hr, 30-40 hrs/wk) converting to full-time after mutual fit is confirmed

    HOW TO APPLY

    Email team[at]allovista.co with:
    1. Your resume or LinkedIn
    2. A brief note on which part of this role excites you most
    3. (Optional) A link to code you're proud of – GitHub, a publication with a methods repo, a pipeline you built

    No cover letter needed. We review every application personally.

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