[Next-Generation Sequencing Book]
  • [Photo] J.W. Bizzaro • August 3, 2000
    ``V. cholerae DNA is split between two circular chromosomes with one holding about three times more of the double-stranded molecule than the other. Researchers speculate that the smaller chromosome may originally have been a free-living organism that was somehow captured. The organism's genetic code has a total of 4,033,460 DNA base pairs, or `letters'. The vast majority of recognisable genes for cell functions and toxicity are found on the large chromosome. The smaller chromosome contains many genes that have come from other organisms distantly related to V. cholerae. Since it was captured, important genes from the larger chromosome have `jumped' on to the smaller one making this structure essential for the organism's survival.''

    Full story at BBC News:
    http://news.bbc.co.uk/hi/english/sci/tech/newsid_863000/863500.stm

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