[Next-Generation Sequencing Book]
  • [Photo] J.W. Bizzaro • August 7, 2000
    ``Numerous bacterial genomes have already been sequenced; with modern industrial sequencers, a new bacterial genome can be sequenced in a few working days. The first draft sequences of the 140000 genes from the human genome should be completed this year, and 3 million single-nucleotide polymorphisms are expected to be documented by 2002. All signal-transduction pathways will probably be elucidated by 2005. The population of Iceland will have their individual genomes sequenced by 2010. The pace of progress is relentless. The next onslaught of data will come from expression databases constructed from every tissue, from the moment of birth through to death. Simultaneously, expression profiles from diseased or pharmacologically challenged tissues will enable us to relate functional genomics to dynamic expression-difference profiles. Most of this work will be performed by commercial genomics companies.''

    Full story:
    http://www.portlandpress.com/biochemist/cyber/0008/default.htm

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