[Next-Generation Sequencing Book]
  • [Photo] J.W. Bizzaro • September 7, 2000
    ``Nobel laureate Dr. Alfred Gilman, chairman of pharmacology at UT Southwestern Medical Center at Dallas, will lead a $10 million-per-year project allowing researchers around the world to pool their efforts in studying one of the biggest unsolved problems in biomedicine – how cells interact with, or signal, each other....The AFCS will help investigators understand the global properties of cellular signaling. The research could lead to the development of a `virtual cell,' a computer program that would mimic the function of a cell, Gilman said. `When we have a complete virtual cell, it can be used as a drug discovery engine to test drugs on the computer, rather than on cells or animals. It would be a wonderful way to understand what the optimal point would be to place a drug to achieve a specific goal in a specific patient in a specific kind of disease,' Gilman said.''

    Full story:
    http://unisci.com/stories/20003/0906001.htm

    And just to rain on their multi-million dollar parade, an Open Source `virtual cell' program has existed for some time, and was even mentioned in Science and Nature:

    E-Cell:
    http://www.e-cell.org

    Reference by Snowdeal.org.

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