[Next-Generation Sequencing Book]
  • [Photo] Gary Van Domselaar • October 30, 2000
    ``Scientists are close to deciphering the makeup of the Y chromosome, that essential core of maleness that's saddled with a bad reputation, a weird past and an uncertain future. It's true, guys: Millions of years from now, your descendants might not have a Y chromosome at all. But first things first. By this winter, scientists hope to have worked out the DNA sequence of the Y chromosome – the identity of its DNA building blocks. They plan to publish their analysis of the sequence sometime next year. The work should help researchers learn about causes of male infertility, because it'll help them identify genes on the Y that men need to make sperm. It should also give a big push to understanding the evolution and functions of the chromosome, a quest that went nowhere for decades until just the 1980s. In fact, one expert says earlier failures to understand the Y have given it a bad rap as a genetic couch potato, and he hopes new DNA studies will finally gain it some respect.''

    Full Story:
    http://www.cnn.com/2000/HEALTH/men/10/30/guy.chromosome.ap/index.html

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