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You betcha:
``Developing Bioinformatics Computer Skills will help biologists, researchers, and students develop a structured approach to biological data and the computer tools they'll need to analyze it. The book covers the Unix file system, building tools and databases for bioinformatics, computational approaches to biological problems, an introduction to Perl for bioinformatics, data mining, data visualization, and tips for tailoring data analysis software to individual research needs.''URL
http://www.oreilly.com/catalog/bioskills/
Tim O'Reilly actually gave the keynote address at BOSC 2000 (followed by Yours Truly).
Reference by Genehack.org (John S.J. Anderson).
Discussion forums: An O'Reilly Book on Bioinformatics?!
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