Opportunity: Research Fellow in GENOMICS and BIOINFORMATICS, Indiana U--Bloomington, IN (US)

Jennifer Steinbachs • October 7, 2005

Opportunity: Research Fellow in GENOMICS and BIOINFORMATICS, Indiana U--Bloomington, IN (US)

Research Fellow - Position #CGB-008
Research Fellow in Daphnia Genomics

The Center for Genomics and Bioinformatics (CGB Indiana University, Bloomington) carries out research in genomics, bioinformatics and is a principle laboratory of the Daphnia Genomics Project. This project creates genomic resources for a developing model organism in ecological and evolutionary genomics research. These resources include a 9-fold sequence coverage of the genome that was produced by the U.S. Department of Energys Joint Genome Institute in collaboration with the Daphnia Genomics Consortium. As a result, Daphnia will soon have the best characterized genome among Crustacea and will ultimately be used to address issues relating to the genome structure of the arthropods.

The CGB has an immediate opening for a Research Fellow to help create and implement algorithms that will rigorously test and help improve the assembly of the genome sequence. The research fellow will also participate in the exploration and interpretation of the data. This position is initially funded for one year and is ideal for investigators who have recently completed their graduate studies in the field of computer science / bioinformatics, or who are in the final stages of completing their dissertations. However, all candidates with expertise in computer programming and prior experience with genome sequencing projects are encouraged to apply, including visiting scientists. We offer a competitive salary ($57,000 plus benefits) and access to state of the art facilities.

Specifically, this project aims to improve the assembly of the Daphnia genome by developing two computational methods for detecting misassembled regions, one based on pattern statistics and another based on clone coverage statistics. These independent algorithms are already proven to accurately detect false assemblies in microbial genome sequencing projects. These two algorithms will be refined and combined to provide a probabilistic support index for scaffold junctions and will function on much larger and more complex eukaryotic genomes, including Daphnia. A significant outcome is the creation and implementation of a support index along localized regions of genome sequence assemblies to indicate regions of high and low confidence.

The position is open now and applications will be accepted until it is filled. Those received by October 31, 2005, will be assured full consideration. Interested candidates may contact (jobs[at]cgb.indiana.edu) for further information.

Please submit a CV and a description of your background and interests, and have three (3) letters of recommendation sent directly to the address below. Be sure to refer to Research Fellow - CGB-008 in your cover letter.

Position #CGB-008
Attn: Research Fellow
Center for Genomics and Bioinformatics
Indiana University
1001 E. 3rd St.
Bloomington IN 47405-3700

Indiana University is an affirmative action equal opportunity employer.

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