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  • [Photo] David Samuels • March 8, 2006

    BACKGROUND

    The Virginia Bioinformatics Institute (VBI) invites applications for an AIDS Therapy Modeler Postdoctoral Associate to work in the research group of Dr. David C. Samuels on a project funded by NIH to study the mitochondrial toxicity of AZT (zidovudine or Retrovir) and other nucleoside analog drugs used in the treatment of HIV/AIDS. For an example of the simulation, see our recent papers in Am. J Physiol. Cell Physiol., vol 288, pp 989-1002, 2005, and in The Biochemical Journal, vol 392, pp 363-373, 2005.

    RESPONSIBILITIES

    The candidate will be involved in computational modeling of the toxicity mechanisms of these drugs, within a biomedical modeling research group and in collaboration with a laboratory group that is carrying out experiments on these drugs. This position will involve further development of the existing simulation, interaction with the lab-based collaborators and supervision of one graduate student.

    REQUIREMENTS

    The successful candidate must have a PhD in a biological, mathematical or computational field; experience in biochemical modeling or cell biology modeling; demonstrated creativity, independence, high motivation, and good communication skills, demonstrated experience in developing publications in peer reviewed high impact scientific journals based on individual research; and possess strong work habits and the ability to work independently as well as with research group.

    PREFERENCES

    Preferences will be given to candidates having knowledge or experience with Mathematica, Systems Biology Markup Language (SBML), or an equivalent modeling or simulation system; or knowledge of mitochondrial biology or of antiviral therapy.

    TERMS

    Duration of the appointment may be up to two years renewable annually dependent on satisfactory performance and continuation of funding. This position will hold the special research faculty rank of Postdoctoral Associate.

    LOCALE

    The Virginia Bioinformatics Institute (VBI) at Virginia Tech has built an internationally recognized scientific program with significant extramural funding. Areas of strength among the 16 research groups at VBI include infectious diseases, ranging from the molecular to the population scale, systems biology approaches to study stress response in several organisms, modeling and simulation of biological networks, functional genomics, metabolomics, proteomics and bioinformatics/computational biology. For a closer look, visit us at http://www.vbi.vt.edu.

    COMPENSATION

    Compensation is commensurate with experience.

    HOW TO APPLY

    Interested candidates should submit a letter of interest and CV upon applying through http://www.jobs.vt.edu searching by posting number 042829. Successful candidates invited for interviews will be required to have three letters of recommendation sent by the author directly to the department as part of the application process.

    DEADLINE

    April 1, 2006. Late applications will only be considered if the position is not filled by that date.

Discussion forums: Opportunity: Post-doc position in biochemical modeling of AZT metabolism @ VBI--Blacksburg, VA (US)

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oppurtunity
Submitted by shradha gupta ; posted on Wednesday, March 8, 2006
SHRADHA GUPTA (M.Sc. Bioinformatics) Institute of Interdisciplinary Studies, Nehru Science Center, University of Allahabad, Allahabad â?? 211016, INDIA. Objective: To do challenging work for a Dynamic Organization that provides ample scope for learning and career advancement through result oriented means in the field of science to become a specialist in Bioinformatics. Completed M.Sc. (Bioinformatics) with 71% from University of Allahabad , India batch 2003-05 Subjects: 1) Maths, 2) Physics, 3) Computer Applications, 4) Statistics, 5) Biochemistry & Biophysics, 6) Molecular Biology & Molecular Genetics, 7) Data Structures through C, 8) Some Concepts of Basic sciences, 9) Fragment Assembly, Gene Mapping & Sequencing of DNA, 10) Biological Data Bases, Search & Analysis, 11) Languages, Algorithms & Tools in Genomics, 12) Molecular structure prediction & Visualization, 13) Molecular Phylogeny & Molecular Evolution, 14) Proteomics & Transcriptomics, 15) Computer Model of Evolution, 16) Computer Aided Drug Designing. Educational qualification: Exam Passed Board/University Year of Passing Subjects Percentage High School I.C.S.E. 1998 Hindi, English, Maths, 79.60 Science, Social Science, Commerce Intermediate I.S.C. 2000 English, Physics, 58.75 Chemistry, Biology B.Sc. University of Pune 2003 Botany, Chemistry, 71.42(Hons.) Zoology Workshops attended: Short-term course on â??Bioinformatics Tools and their Applicationsâ?? at Department of Biochemical Engineering & Biotechnology, IIT New Delhi. Projects: 1. Mini project under the guidance of Prof. A.K. Gupta, Coordinator Bioinformatics Program, University of Allahabad. The topic was â??Protein Structure prediction through Molecular Dynamics using the software GROMACS â??. Dissertation work: Structure prediction of 5-hydroxy Tryptophan using NMR Spectroscopy Skills: Programming â?¢Operating systems: MS-DOS, Windows 98 / XP/NT â?¢ Programming Languages: C, C++ and Perl â?¢ Packages: MS Office 2003, Adobe Packages . Software Package: Matlab â?¢ Web based programming: HTML Bioinformatics softwareâ??s & tools â?¢ Molecular Visualization Software: Rasmol, Cn3D, VMD, Swiss PDB Viewer â?¢ Alignment Tools: BLAST, FASTA, ClustalW package â?¢ Phylogeny package: Treecon, Phylip. Wet lab â?¢ Biochemistry: Qualitative and quantitative test of protein and carbohydrate. â?¢ Analytical: SDS-PAGE, Agarose Gel Electrophoresis Delivered Seminars: 1. Biological software Applicable in Bioinformatics. 2. DNA Micro Array Other Relevant Information: 1. Working Model & Poster presentation in Nehru Science center, University of Allahabad on the eve of Science day. 2. Chief Editor of departmental annual scientific magazine â??Bioinformatics Gatewayâ??. Personal Details: Fatherâ??s Name: Mr. Jeevan Gupta Motherâ??s Name: Mrs. Saroj Gupta Date of Birth: February 18, 1983 Nationality: Indian Sex: Female Linguistic Proficiency: English, Hindi and Marathi Permanent address: 22/25 Himmat Ganj, Purshottam Nagar, Allahabad â?? 211016, (U.P.), INDIA Contacts: 0532-2615624 Mobile No: 9415283904 E-mail: army-shradha@yahoo.co.in PLACE: Allahabad DATE: (Shradha Gupta) REFERNECES: 1. Prof. A. K. Gupta Head, Department of Electronics and Communication, J.K.Institute of Applied Physics and Technology, Coordinator M.Sc. Bioinformatics Program, University of Allahabad. Allahabad-211002. 2. Prof. D.K. Gupta Head, Department of Biochemistry, Co-coordinator M.Sc. Bioinformatics Program, University of Allahabad, Allahabad-211002. 3. Dr. Shanthy Sundaram Reader, Center for Biotechnology, University of Allahabad, Allahabad-211002.

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