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GenomeWeb: Lander Lashes Out Against Celera's Sequencing Method, Outlines Plans
Submitted by Gary Van Domselaar; posted on Thursday, March 29, 2001
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"CAMBRIDGE, Mass., March 27 - Eric Lander, director of the Whitehead/MIT Genome Sequencing Center and a key figure in the publicly-funded effort to sequence the human, sharply criticized Celera's whole genome sequencing method on Tuesday, saying there 'is no evidence' the approach worked.
"Addressing Harvard's Genomics 2001 conference in the keynote speech, Lander, who also discussed current public projects, said Celera used the Human Genome Project's sequence data, which contained about 90 percent of the sequence of the genome, for input into its whole genome shotgun assembler.
" 'If you use a source of data with 90 percent of the genome, put it in, and get 90 percent at the end, one does occasionally wonder where the beef is,' Lander said. 'At the moment there is no evidence that the whole genome shotgun method worked at all for the human genome.'
"Nevertheless, Lander said that researchers from the Human Genome Project and Celera were still planning to meet for a workshop to compare and analyze the data. The workshop was first proposed when the two groups published their papers in February."
Full Story:
http://www.genomeweb.com/articles/view-article.asp?Article=2001328101413
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