[Next-Generation Sequencing Book]
  • [Photo] Joan Yantko • July 12, 2006
    Comparative Genome Analyses of Bacterial Genomes and Applications

    LOCALE: Stanford University, California
    DATES: August 14-18, 2006

    BACKGROUND

    The world-wide genome sequencing efforts have produced roughly 400 complete bacterial genomes, and this number is expected to extend beyond 10,000 within the next few years. As the pool of complete bacterial genomes rapidly grows, comparative genomic analysis surfaces as one of the most important classes of tools both for mining the genomes and for studying bacterial biology and evolution at a systems level. The community urgently needs more powerful methodologies, tools, and application protocols to help address fundamental biological problems related to the mechanisms of bacterial genome evolution and associated areas of research.

    TOPICS

    Invited scientists from leading research centers and laboratories will present their work in the field of comparative genomic analysis, particularly for the study of bacterial biology and evolution, which may cover but may not be limited to the following topics:
    • Modeling phylogenetic and environmental diversities of bacterial genomes and its application to the design of comparative genomic analysis
    • Prediction and analysis of homologous/orthologous genes with the presence of uncertainty and noise
    • Prediction and analysis of cis-regulatory elements and their homologs/orthologs across bacterial genomes
    • Prediction and analysis of high-level genomic structures (e.g., operons, uber-operons, and regulons) and their homologs/orthologs across different bacterial genomes
    • Prediction and analysis of biological networks/pathways and their homologs/orthologs across different bacterial genomes
    • Evolution and adaptation of bacterial genomes
    • Computational issues

    AIM & SCOPE

    The workshop is aimed at eliminating barriers and providing a platform for researchers from different disciplines to exchange visions, insights, ideas, and discoveries about the challenges and opportunities in the field, to share and appreciate research efforts that have been devoted to the field, to provide and seek advice/suggestion/solutions to some problems in the field, and to establish face-to-face collaboration.

    FOR MORE INFORMATION

    For details, visit: http://www.lifesciencessociety.org/CSB2006/

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