BACKGROUND:
The University of Cape Town National Bioinformatics Network Node was set up to develop Bioinformatics at the university. The Node is responsible for Bioinformatics education, research and services. Service provision includes the development of a Bioinformatics support platform for genomics and proteomics, and the Node provides support for researchers in Microarray data analysis.

RESPONSIBILITIES

The position involves research into the development of new and/or application of existing analytical tools for the analysis of microarray data. In addition, the incumbent will be expected to provide statistical advice and analytical services to scientists conducting DNA microarray experiments at UCT and elsewhere in South Africa. The majority of clients use cDNA-based glass arrays but it is envisaged that several researchers will need analytical advice and help in analysing high-density oligonucleotide and protein array data. Experience in using R-Bioconductor would be advantageous, as many consultations will typically involve the construction of R scripts for a particular analysis. Additional to the consulting and support aspects of the role, it also involves research into the development of new tools for design and analysis of oligonucleotide and cDNA-based glass slide arrays as well as some analytical training.

REQUIREMENTS:
The position requires experience with microarray data analysis, statistical principles and familiarity with MIAME standards for microarray experiments. A solid knowledge of microarray design, pre-processing methods, differential expression and clustering is essential. Good communication skills are essential for communicating statistical principles and methodology to biological researchers.

PREFERENCES:
Researchers with experience in microarray data analysis.

LOCALE:
Cape Town, South Africa

HOW TO APPLY:
Send CV and covering letter to info[at]cbio.uct.ac.za

DEADLINE:
September 2006