[Next-Generation Sequencing Book]
  • [Photo] Karen Kohlhepp • August 24, 2006

    ABOUT US

    Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co. Inc., develops and implements technologies that will improve drug discovery. The company's leading-edge genomic research and data analysis efforts focus on how medical compounds affect biology, enabling more accurate selection of drug targets and more efficient drug development.

    RESPONSIBILITIES

    A postdoctoral position is available at Rosetta that will focus on developing and applying computational systems biology approaches to elucidate and utilize biological pathways in drug discovery. Research topics include developing and applying approaches to
    • Ascertain the mechanisms and pathways underlying gene and protein expression patterns.
    • Predict effects of perturbations such as siRNA knockdown or compound interactions using protein-protein interaction and/or gene regulatory networks models.
    • Identify mechanism-based biomarkers using high throughput genomic data and clinical endpoints.
    This postdoctoral position will be hosted by the Informatics department at Rosetta and is jointly sponsored by Robert Gentleman, Fred Hutchinson Cancer Research Center Program in Computational Biology. Comprehensive pathway databases, the world's largest expression data respository, RNAi technologies, access to clincal samples with rich clinicial data, collaborative interactions with a critical mass of informatics and bioinformatics scientists, and state of the art computational facilities are some of the resources that will be available to the successful candidates.

    REQUIREMENTS

    Qualifications include: Ph.D. in bioinformatics or related field with solid background in molecular biology, computer science, and statistics. Solid training in data analysis algorithms is essential. Background in oncology or metabolic disease is desirable, as is experience in systems biology, pathways or network bioinformatics. Applicants should have demonstrated excellence in one or more of these areas, including a strong publication record.

    HOW TO APPLY

    To be considered for this position, please visit our career site at http://www.rii.com/jobs under Postdoctoral Opportunities to submit your resume. Rosetta is an equal opportunity employer, M/F/D/V – proudly embracing diversity in all of its manifestations.

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