ABOUT US

Zymeworks Inc. is a Canadian biotechnology company that is developing predictive computational technology for protein engineering.

As a growing company, we are looking for exceptionally bright and motivated individuals who are eager to showcase their talent, experience and leadership in a team environment. To learn more about the Company, please visit our web site at http://www.zymeworks.com.

Currently, we are seeking an enzyme engineer to take part in in silico enzyme modification projects and actively participate in the development and validation of our in-house molecular simulation software. The successful applicant for this position will start in March of 2007.

REQUIREMENTS: (Applicants will not be considered without the following skills)
• Ph.D. in Molecular Biology or Biochemistry
• Demonstrated experience in rational protein design or directed evolution
• Thorough knowledge and practical experience of structural biology and enzyme mechanisms
• Greater than 2 years of either industrial or academic post-graduate experience in a protein biochemistry-related field
• Ability to communicate in the English language (spoken and written)

Further skills (The following skills are an asset to qualified applicants)
• Familiarity with wet-lab techniques and processes for enzyme modification, expression, purification and biochemical characterization
• Experience with homology modeling and docking software
• Experience using molecular modeling and visualization packages (AMBER, CHARMM, VMD, Chimera, etc.)
• Knowledge of the Linux operating system
• Experience in one or more scripting languages (Perl, Tcl, etc.)
• General understanding of the software development process
• Should know about: AAGGAGAACGATCGTGAATGG

RESPONSIBILITIES

• Perform feasibility studies for proposed protein engineering projects
• Propose and carryout internal projects for software validation
• Write analysis tools in the perl and Tcl/Tk scripting languages
• Closely interact with the software development team to improve and advance the functionality of our in-house modeling/analysis package
• Assist in the selection of commercial software tools to supplement our in-house package
• Participate in the preparation of patents and publications

COMPENSATION

Salary and benefits are commensurate with experience and are highly competitive with industry standards.

HOW TO APPLY

If you are interested in applying for this position, please email your curriculum vitae and cover letter to jobs[at]zymeworks.com with 1220: Enzyme Engineering in the subject line.

Due to the high volume of applicants, only candidates selected for an interview will be contacted.