[Next-Generation Sequencing Book]
  • [Photo] J.W. Bizzaro • May 8, 2007
    LOCALE: Online
    DATES: May 21-25, 2007

    OBJECTIVE

    With systems biology budding as a discipline, there is a colossal need for biologists to understand the interactions within biological networks. There has been much talk about systems biology and protein-protein interactions (PPI), and this course will dig into some of the fundamental issues concerning PPIs, their need and usage. The exercises and take-home messages will encourage students to give some thought to the topics covered and hopefully build some excitement about the field of systems biology. Nevertheless, this course shouldn't be considered too difficult for beginners.

    TOPICS

    • Bioinformatics to systems biology: essential ascent
    • The what and the hows of PPIs: a computational biologist's perspective
    • Why systems biology? computational systems biology vs. molecular systems biology
    • Assays, tools and techniques in PPIs: pros and cons
    • Types of interactions and networks
    • Data validation and integration
    • Capabilities of networks
    • A look at PPI data
    • Future challenges
    • Introduction to Cytoscape: brief exercise
    • Networkology: data representations
    • Exercises with iHOP, String, Bind, PreBind
    • Exercises with Genecards, MINT, HPRD
    This course is taught in collaboration with Roskilde University, Denmark.

    FOR MORE INFORMATION

    Visit http://edu.bioinformatics.org/CC

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