BACKGROUND

Computercraft seeks a computational biologist with a background in genotype analysis to work with NCBI scientists to develop infrastructure to analyze large-scale genomic data with clinical phenotype data. The successful candidate will work onsite at the National Center for Biotechnology Information (NCBI) in the Genotype and Phenotype database group http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gap . This groundbreaking project is aimed to assist scientists discover associations between genetic variants and risks for disease.

RESPONSIBILITIES

Responsibilities will include genotype analysis pipeline development, data reformatting, data quality control, management of a relational database, data curation, and communication with external investigators. This is an opportunity to be involved in the development of a new resource with the potential to revolutionize human genetic disease research.

REQUIREMENTS

• Ph.D. or M.S. or sufficient experience in genetic linkage analysis and/or allelic association studies
• Scripting experience in Perl
• Relational database experience (SQL)
• Linux/UNIX experience
• Ability to work with a team in a production environment and communicate well with NCBI biologists and programmers as well as external scientists
• Strong interest in contributing to the development of public database resources

Other Desirable Experience:
• Human genetics
• Haplotypes
• Analysis of structural variations
• Copy number variation
• Linkage disequilibrium
• QA filtering of genotype data (HWE, non-Mendelian segregation)
• PedCheck, Aspex, MERLIN, CRIMAP
• C++
• XML/XSLT
• HTML/CGI
• Experience with dbSNP

HOW TO APPLY

For consideration please submit cover letter, curriculum vitae, salary history, salary requirements, and U.S. employment eligibility (you must currently reside in the U.S. and be eligible to work). Please note that incomplete application cannot be considered.

Attn: HR
8300 Greensboro Drive
Suite 720
McLean VA 22102
703.288.4679 fax
hr[at]computercraft-usa.com
http://www.computercraft-usa.com

Computercraft offers a competitive salary and an excellent benefits package including PPO health insurance with 100% company paid premiums, 401K program with matching, paid time off and holiday pay, life insurance, flexible spending and disability coverage. We offer an excellent work life balance with a standard 40 hour work week and the chance to work alongside accomplished scientists at NIH/NCBI.

Computercraft is an equal opportunity employer.