[Next-Generation Sequencing Book]
  • [Photo] Ron Hart • November 11, 2007
    BACKGROUND: Seeking qualified candidate to join my research group, focused on the molecular mechanisms underlying neural differentiation, particularly from human embryonic stem cells. Our recent work uncovered patterns of microRNA and mRNA changes during differentiation in rat neural precursors, human ES cells, and human MSC (see lab web site http://www.ngelab.org). Proposed projects include the use of a new Applied Biosystems SOLiD (next-gen) sequencing system to identify novel microRNAs expressed during neural specification in human ES cells. We use bioinformatics to extract both general patterns and specific examples for hypothesis-driven laboratory experiments using standard techniques of molecular biology. Our goal is to learn how to program stem cells to develop therapeutic transplants for spinal cord injury and related conditions.

    RESPONSIBILITIES: The successful candidate will work with a team to plan experiments and create libraries from samples, manage the retrieval of datasets from the service lab, perform genomic alignments and statistical analyses of data, complete biological interpretation of results, and prepare manuscript figures and draft text for submission.

    REQUIREMENTS: A recent Ph.D. in molecular biology and/or bioinformatics is required. At this time we can only consider U.S. citizens or holders of a valid green card.

    PREFERENCES: Experience with basic molecular biology methods (e.g., PCR, microarrays, promoter studies, regulated expression systems) stem cell culture techniques is preferred. Knowledge of bioinformatics methods related to gene expression studies (such as R/BioConductor) is preferred, as is programming experience with SQL, PHP and/or PERL/BioPERL.

    TERMS: A two-year commitment is generally expected.

    LOCALE: My laboratory is part of the W.M. Keck Center for Collaborative Neuroscience (http://keck.rutgers.edu) and the Rutgers Stem Cell Research Center (http://scrc.rutgers.edu), both located on the Busch campus of Rutgers University in Piscataway, in a highly collaborative and active environment. We are a short train ride from New York City or Philadelphia.

    COMPENSATION: Postdoctoral associates are generally paid higher than NIH scales. Rutgers offers a generous benefits package.

    HOW TO APPLY: Please register and submit your application online at: http://cord.rutgers.edu/postdoc/apply?p=4

    DEADLINE: The position is available immediately and will be filled as soon as possible.

Discussion forums: Opportunity: Postdoctoral Associate in Neural Stem Cell Genomics at Rutgers--Busch campus, Piscataway, NY (US)

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