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URL: Systems biological approach to cell behavior and cancer
Submitted by Sidharth Mohandas; posted on Thursday, November 15, 2007
When there is something wrong with the fruit, the best approach is to go to the root. And that's exactly what we're trying to do here at RRL. Getting to the molecular level and finding out which signaling pathways and molecular interactions are responsible for the formation and development of cancer. If you would have noticed in the pathway explanations I have put up in our site: activation of small signaling pathways is what leads to such a dreadful disease.
So what we need is a complete database of molecular interactions that will lead to cancer – either by activation of cell proliferation or by inhibition of apoptosis, which ever way it is. This is what we call the systems biological approach to cancer. With such a big database as our source, we can try all given possibilities that can lead to cancer on a computational model.
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