[Next-Generation Sequencing Book]
  • [Photo] Ashley Lindenmuth • July 11, 2008
    Yale University offers exciting opportunities for achievement and growth in New Haven, Connecticut. Conveniently located between Boston and New York, New Haven is the creative capital of Connecticut with cultural resources that include three major museums, a critically-acclaimed repertory theater, state-of-the-art concert hall, and world-renowned schools of Architecture, Art, Drama, and Music.

    RESPONSIBILITIES

    Provide management and high level technical automation skills to the new Yale Center for High Throughput Biology. Formulate and execute research plans relating to the set up and improvement of the HTS suite and related areas. Propose budgets; manage staff. Design, build and continually maintain several robust and flexible automated high-throughput screening platforms. Research and stay current with new technological advances in the field and recommend new technology and processes to the Director.

    Position Description:
    • Maintain an inventory of resources related to the HTS section and continually re-stock on consumables in a timely and cost efficient manner. Provide the information and practical assistance to informatics partners needed to establish an integrated LIMS (lab information management system).
    • Negotiate contracts for maintenance and support against a pre-set budget.
    • Conduct research of similar fields and recommend best practice for work relating to HTS. Keep up-to-date on advances in technology and make recommendations for new processes and technology.
    • Perform chemical screens in conjunction with lead scientists in an efficient, validated, modular manner, on time and within budget.
    • Perform siRNA screens in conjunction with lead scientists in an efficient, validated, modular manner, on time and within budget.
    • Perform Lentivirus production development in conjunction with lead scientists in an efficient, validated, modular manner, on time and within budget.
    • Perform Adenovirus production development in conjunction with lead scientists in an efficient, validated, modular manner, on time and within budget.
    • Forecast time frames for projects, upgrades, maintenance and other HTS related activities.
    • Generate daughter libraries of master compounds, Lenti and Adeno virus libraries in accordance with safety handling procedures and scientific protocols.
    • Document each process and project in a modular fashion including modular SOPs. Provide technical assistance on high throughput automation and equipment maintenance, as requested.
    • Present data at meetings and presentations in written and oral formats.
    • Verify and maintain accuracy of data and records about use of reagents such as compound libraries and siRNA libraries; submit reports to the Director in a timely fashion.
    • Use funds available from cost-savings generated within the HTS section to improve process and technology. Propose budget for projects and ongoing maintenance to Director.
    • Plan and execute an annual budget for HTS in conjunction with the Director and business manager.
    • Manage present and future staff; make recommendations about staffing.
    REQUIREMENTS:
    • Master's Degree in Chemistry, Biology, Biochemistry or other related discipline and three years of experience; or an equivalent combination-of experience and education.
    • Master’s or Bachelor’s Degree in automation, robotics, computers or related or equivalent work experience.
    • Preferred: Project and staff management experience.

    HOW TO APPLY

    For more information and immediate consideration, please apply online at http://www.Yale.edu/jobs - the STARS req ID for this position is 5011BR. Please be sure to reference source code XXXXX when applying for this position.

    We invite you to discover the excitement, diversity, rewards and excellence of a career at Yale University. One of the country's great workplaces, Yale University offers exciting opportunities for meaningful accomplishment and true growth. Our benefits package is among the best anywhere, with a wide variety of insurance choices, liberal paid time off, fantastic family and educational benefits, a variety of retirement benefits, extensive recreational facilities, and much more.

    Yale University is an affirmative action/equal opportunity employer. Yale values diversity in its faculty, staff, and students and strongly encourages applications from women and members of underrepresented minority groups.

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