[Next-Generation Sequencing Book]
  • [Photo] Ashley Lindenmuth • July 11, 2008
    Yale University offers exciting opportunities for achievement and growth in New Haven, Connecticut. Conveniently located between Boston and New York, New Haven is the creative capital of Connecticut with cultural resources that include three major museums, a critically-acclaimed repertory theater, state-of-the-art concert hall, and world-renowned schools of Architecture, Art, Drama, and Music.

    RESPONSIBILITIES

    Collaborate with the Director of the Center in setting priorities for project development and expansion. Research and develop ideas for improvement of existing HTS equipment. Play a significant role in the development and ongoing implementation of scientific and operational plans for the HTS section. Participate in the design of projects. Establish reports relating to the work performed for each project involving the HTS suite and submitting them in a timely fashion. Responsible for maintaining and updating comprehensive SOP’s relating to the different procedures and protocols uses, implemented and/or developed in the HTS section. Have limited management of staff.

    The Yale Center for HTS Biology performs automated high-throughput screening (HTS) on biological assays.

    Position Description:
    • Continually maintain several robust and flexible automated high-throughput screening platforms.
    • Provide information and practical assistance to our informatics partners on a need-to basis as required to establish an integrated LIMS.
    • Work with biologists and informatics in the Center to generate high quality products.
    • Perform chemical screens in conjunction with lead scientists in an efficient, validated, modular manner.
    • Perform siRNA screens in conjunction with lead scientists in an efficient, validated, modular manner.
    • Perform Lentivirus production development in conjunction with lead scientists in an efficient, validated, modular manner.
    • Perform Adenovirus production development in conjunction with lead scientists in an efficient, validate, modular manner
    • Generate daughter libraries of master compounds, Lenti and Adeno virus libraries in accordance with safety handling procedures and scientific protocols.
    • Maintain an inventory of resources related to the HTS section and continually re-stock consumables in a timely and cost efficient manner.
    • Conduct research of similar fields and recommend best practice for work relating to HTS.
    • Forecast time frames for projects, upgrades, maintenance and other HTS related activities.
    • Verify and maintain accuracy of data, records of use of reagents such as compound libraries and siRNA libraries; submit reports to the Director in a timely fashion.
    • Document each project in a modular fashion including modular SOPs

    REQUIREMENTS

    • Master's Degree in Chemistry, Biology, Biochemistry or other related discipline and one year of experience; or an equivalent combination of experience and education.
    • Experience with high-throughput screening on biological assays.

    HOW TO APPLY

    For more information and immediate consideration, please apply online at http://www.Yale.edu/jobs - the STARS req ID for this position is 5012BR. Please be sure to reference source code IBIOI when applying for this position.

    We invite you to discover the excitement, diversity, rewards and excellence of a career at Yale University. One of the country's great workplaces, Yale University offers exciting opportunities for meaningful accomplishment and true growth. Our benefits package is among the best anywhere, with a wide variety of insurance choices, liberal paid time off, fantastic family and educational benefits, a variety of retirement benefits, extensive recreational facilities, and much more.

    Yale University is an affirmative action/equal opportunity employer. Yale values diversity in its faculty, staff, and students and strongly encourages applications from women and members of underrepresented minority groups.

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