[Next-Generation Sequencing Book]
  • [Photo] Edie Estabrook • November 10, 2008

    RESPONSIBILITIES

    Proteostasis Therapeutics, Inc. is seeking highly motivated individuals interested in applying computational and bioinformatic approaches to drug discovery. The research interest is focused on developing/applying innovative data analysis capabilities to gain insights into gene networks involved in proteome homeostasis and protein mis-folding and investigate their disease relevance. High-throughput biological datasets such as microarray data, protein-protein interaction data, RNAi data will be explored and integrated. This scientist will be part of a bioinformatics team working closely with cross-discipline teams including biology and medicinal chemistry.

    REQUIREMENTS

    • Proficiency in large-scale biological, “-omics” data analysis. Broad experience with microarray analysis required.
    • Working knowledge of systems biology (pathways, networks, etc) and sequence analysis.
    • Knowledge and experience in machine learning and data mining is preferred.
    • Proficiency in R, matlab, or equivalent statistical software.
    • Strong background in statistical analysis.
    • Good programming skills in Java, Perl, Python or C, can independently manipulate large datasets.
    • Familiarity with relational databases (SQL).
    • Good understanding of data analysis methods and experimental design.
    • Highly analytical with good technical and problem solving skills.
    • Excellent written and verbal communication skills.
    Recent Ph.D in bioinformatics, computational biology, or computer science/electrical engieerng with exposure to life sciences. A strong publication record is essential. Postdoctoral experience or biotech/pharmaceutical industry experience is a plus.

    LOCALE: Cambridge, MA

    HOW TO APPLY

    Submit resume to info[at]proteostasis.com

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