[Next-Generation Sequencing Book]
  • [Photo] Debbie Higdon • January 6, 2010

    BACKGROUND

    SAIC-Frederick, Inc., is a wholly owned subsidiary of Science Applications International Corporation (SAIC). As prime contractor for the National Cancer Institute’s research and development center in Frederick, MD, this national laboratory is dedicated to rapidly translating basic research into new technologies for diagnosing, treating, and preventing cancer and AIDS. SAIC-Frederick maintains a full suite of advanced technologies in areas such as nanotechnology, genomics and imaging; operates the federal government’s only drug and vaccine manufacturing facilities; operates the high-performance Advanced Biomedical Computing Center; and supports more than 300 clinical trials for patients in the US and around the world.

    RESPONSIBILITIES

    The Developmental Therapeutics Program's primary emphasis is on drug discovery and characterization, identification of new therapeutic molecular targets and participation in the evaluation of samples and results from animal models with a goal of identifying drugs with potential therapeutic value. Research within the Target Structure Based Drug Discovery Group on the therapeutic discovery effort for cancers and mechanism of actions of many Class A biothreat agents using computational biology. Both of these efforts utilize targets common to apoptosis such as kinases and phosphatases. The analysis and informatics approach for relevant systems biological explorations has become a new priority in this program. A principal part of this mission includes the creation of hypotheses to investigate cellular pathways to uncover new targets that eventually will support small molecule combination strategies as countermeasures.

    REQUIREMENTS

    • Possession of a Bachelors degree in biomedical science/bioinformatics/math/computer related field from an accredited college or university or four (4) years related experience in lieu of degree
    • Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States.
    • In addition to education requirements, a minimum of four (4) years related experience in a laboratory environment with a strong background in database management or utility programming
    • Must have experience in molecular/cell biology, an understand mechanisms of synthetic lethality. Have technical proficiency in R/Bioconductor software
    • Be able to utilize scripting language(s) such as Perl or Python
    • Be familiar with Unix computing and programming environment
    • Understand issues and techniques in systems biology
    • Be familiar with pathway tools such as Ingenuity Pathways Analysis or Ariadne Pathway Studio
    • This position is subject to obtaining a Public Trust Clearance.
    LOCALE: Frederick, MD 21702

    SALARY & COMPENSATION

    Excellent salary and benefits accompany our position. For immediate consideration, please apply online for position #163978 at our website: http://www.saic-frederick.com

    HOW TO APPLY

    Apply online at http://www.saic-frederick.com

    DEADLINE: N/A

    SAIC is an equal opportunity employer and values cultural diversity in the workplace.

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